Role of oxidative stress after routine Iron supplementation in normal and anemic women during pregnancy: Central Indian scenario

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dc.contributor.authorKumar, Ajaien_US
dc.contributor.authorJawad, Kalbeen_US
dc.contributor.authorSingh, Seemaen_US
dc.contributor.authorSharma, Pradeepen_US
dc.contributor.authorSingh, Niranjanen_US
dc.contributor.authorGupta, Mrinalen_US
dc.date.accessioned2020-09-24T07:34:32Z
dc.date.available2020-09-24T07:34:32Z
dc.date.issued2019-02
dc.description.abstractIron deficiency anemia (IDA) is one of the most common nutritional disorders worldwide, affecting people of all ages in developed and developing countries. causes dimunition of various antioxidant enzymes like superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase. The objective of the study was to detect impact of iron supplementation in anaemic & non- anaemic pregnant subjects on oxidative stress. Patients are divided into two groups, Control groups (60 non-anemic pregnant women) & Study groups (60 anemic pregnant women). The blood sample (5 ml) was collected from different groups of subjects. In controls groups, a fall in catalase, superoxide dismutase, glutathione peroxidase and glutathione reductase were seen while lipid peroxidase was found to have increased significantly after iron therapy. In study group, and increment in all markers except lipid peroxidase was seen and the level of lipid peroxidase was decreased following iron supplementation which was statistically significant (p<0.001). it may be concluded that iron deficiency anaemia is associated with free radical generation and peroxidation of vital body molecules which implies increased risk for pregnant women.en_US
dc.identifier.affiliationsDepartment of Biochemistry, King George Medical College, Lucknow, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Uttar Pradesh University of Medical Science, Saifai, Etawah, Indiaen_US
dc.identifier.affiliationsDepartment of Respiratory Medicine, King George Medical College, Lucknow, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Uttar Pradesh University of Medical Science, Saifai, Etawah, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Uttar Pradesh University of Medical Science, Saifai, Etawah, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Uttar Pradesh University of Medical Science, Saifai, Etawah, Indiaen_US
dc.identifier.citationKumar Ajai, Jawad Kalbe, Singh Seema, Sharma Pradeep, Singh Niranjan, Gupta Mrinal. Role of oxidative stress after routine Iron supplementation in normal and anemic women during pregnancy: Central Indian scenario. International Journal of Research and Development in Pharmacy & Life Sciences (IJRDPL). 2019 Feb; 8(1): 21-24en_US
dc.identifier.issn2281-0238
dc.identifier.issn2393-932X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203833
dc.languageenen_US
dc.publisherSociety for research and Development in Educationen_US
dc.relation.issuenumber1en_US
dc.relation.volume8en_US
dc.source.urihttps://doi.org/10.21276/IJRDPL.2278-0238.2019.8(1).21-24en_US
dc.subjectIron deficiencyen_US
dc.subjectanemiaen_US
dc.subjectOxidative stressen_US
dc.subjectsuperoxide dismutaseen_US
dc.titleRole of oxidative stress after routine Iron supplementation in normal and anemic women during pregnancy: Central Indian scenarioen_US
dc.typeJournal Articleen_US
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International Journal of Research and Development in Pharmacy and Life Sciences