Biotin deficiency causes alterations in glycosaminoglycans and glycoproteins in rat aorta.

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1993-02-01
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Abstract
Biotin deficiency produced by feeding raw egg white caused decrease in the concentration of many glycosaminoglycans (GAG) in the aorta in rats fed standard laboratory diet and atherogenic diet. This decrease has been observed to be due to the increased activity of enzymes involved in the degradation of GAG and glycohydrolases which cleave the carbohydrate components of glycoproteins.
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Abraham A, Kurup PA. Biotin deficiency causes alterations in glycosaminoglycans and glycoproteins in rat aorta. Indian Journal of Experimental Biology. 1993 Feb; 31(2): 151-5