Combination antifungals as an effective means of salvage in paediatric leukaemia patients with invasive fungal infections

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dc.contributor.authorMeena, JPen_US
dc.contributor.authorGupta, AKen_US
dc.contributor.authorJana, Men_US
dc.contributor.authorSeth, Ren_US
dc.date.accessioned2020-04-23T07:37:46Z
dc.date.available2020-04-23T07:37:46Z
dc.date.issued2019-03
dc.description.abstractInvasive fungal infections (IFIs) are an important cause of morbidity and mortality in paediatric leukaemias. Antifungal combinations to treat these patients are being explored. Fourteen children with leukaemias and IFIs were treated with a combination of antifungal agents at our centre. The first antifungal was amphotericin-B in 13 children and voriconazole in one child. In view of no improvement and clinical deterioration, in nine patients, voriconazole was added as the second antifungal agent and in four, it was caspofungin. All patients completed 4�weeks of antifungal therapy. The overall mortality attributable to IFI for the cohort was 4/14 (28%).en_US
dc.identifier.affiliationsDepartment of Pediatrics, Division of Pediatric Oncology, All Institute of Medical Sciences, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartment of Radiology, All Institute of Medical Sciences, New Delhi, Indiaen_US
dc.identifier.citationMeena JP, Gupta AK, Jana M, Seth R. Combination antifungals as an effective means of salvage in paediatric leukaemia patients with invasive fungal infections. Indian Journal of Medical Microbiology. 2019 Mar; 37(1): 109-112en_US
dc.identifier.issn0255-0857
dc.identifier.issn1998-3646
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/198846
dc.languageenen_US
dc.publisherIndian Association of Medical Microbiologistsen_US
dc.relation.issuenumber1en_US
dc.relation.volume37en_US
dc.source.urihttps://dx.doi.org/10.4103/ijmm.IJMM_18_157en_US
dc.subjectCombination antifungalsen_US
dc.subjectleukaemiasen_US
dc.subjectpaediatricsen_US
dc.titleCombination antifungals as an effective means of salvage in paediatric leukaemia patients with invasive fungal infectionsen_US
dc.typeJournal Articleen_US
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