Pantoprazole Induced Black Hairy Tongue: A Case Report

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dc.contributor.authorKrishnan, Divya Gen_US
dc.contributor.authorDaud, Shaikh Ubedulla Shaikh Iqbalen_US
dc.contributor.authorAnukeshVasuKelothen_US
dc.contributor.authorP, Neethuen_US
dc.date.accessioned2024-09-24T08:06:49Z
dc.date.available2024-09-24T08:06:49Z
dc.date.issued2023-08
dc.description.abstractIntroduction: Black Hairy Tongue (BHT) is characterized by abnormally hypertrophied and elongated filiform papillae, resulting in a blackish discoloration on the dorsal surface of the tongue. BHT has been reported as an adverse drug reaction to various categories of drugs. Nevertheless, cases of Pantoprazole-induced BHT have been rarely reported. Case Description: We present a case involving a 42-year-old female who was admitted to the Surgery ward due to postoperative wound infection. She had been prescribed oral Clarithromycin and Pantoprazole. On the third day of initiating these medications, she reported experiencing a blackish discoloration on the dorsal surface of her tongue along with a change in her sense of taste. Clinical and microscopic examinations led to a diagnosis of Black Hairy Tongue (BHT). There was a suspicion that BHT might be an adverse drug reaction specifically to Pantoprazole. Consequently, the administration of Pantoprazole was ceased, while Clarithromycin continued for the full prescribed course. The patient received guidance to scrape her tongue thrice daily, maintain proper hydration, and adhere to good oral hygiene practices. By the third day following the discontinuation of Pantoprazole, the black discoloration and taste alterations had completely resolved. Causality assessment using the WHO-UMC (World Health Organization - Uppsala Monitoring Centre) scale indicated a 'probable' association between the adverse drug reaction and Pantoprazole. Conclusion: Physicians need to be vigilant about the potential occurrence of Black Hairy Tongue (BHT) in patients using Pantoprazole, and they should recognize that discontinuing the medication, coupled with mechanical debridement and maintaining proper oral hygiene, leads to complete resolution of the condition.en_US
dc.identifier.affiliationsDepartment of Pharmacology, KMCT Medical College, Kerala University of Health Sciences, Kerala, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, KMCT Medical College, Kerala University of Health Sciences, Kerala, Indiaen_US
dc.identifier.affiliationsDepartment of Surgery, KMCT Medical College, Kerala University of Health Sciences, Kerala, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, KMCT Medical College, Kerala University of Health Sciences, Kerala, Indiaen_US
dc.identifier.citationKrishnan Divya G, Daud Shaikh Ubedulla Shaikh Iqbal, AnukeshVasuKeloth, P Neethu. Pantoprazole Induced Black Hairy Tongue: A Case Report. International Journal of Medical Research & Health Sciences. 2023 Aug; 12(8): 20-24en_US
dc.identifier.issn2319-5886
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/231000
dc.languageenen_US
dc.publisherSumathi Publicationsen_US
dc.relation.issuenumber8en_US
dc.relation.volume12en_US
dc.source.urihttps://www.ijmrhs.com/medical-research/pantoprazole-induced-black-hairy-tongue-a-case-report-100944.htmlen_US
dc.subjectBlack Hairy Tongue (BHT)en_US
dc.subjectPantoprazoleen_US
dc.subjectAdverse drug reactionen_US
dc.subjectSurgical wound infectionen_US
dc.titlePantoprazole Induced Black Hairy Tongue: A Case Reporten_US
dc.typeJournal Articleen_US
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