Dengue Serotypes In Manipur –Findings From A Retrospective Analytical Study In A Tertiary Care Hospital

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dc.contributor.authorAnand Singh, Len_US
dc.contributor.authorSuson, Ten_US
dc.contributor.authorGeeta, Chanu Cen_US
dc.contributor.authorRanjana, Devi Ken_US
dc.contributor.authorRebachandra, Singh Hen_US
dc.date.accessioned2024-09-24T08:09:51Z
dc.date.available2024-09-24T08:09:51Z
dc.date.issued2023-12
dc.description.abstractObjectives:As a part of an ongoing research programme on vector-borne viral diseases especially Dengue, a retrospective analytical study on the occurrence and distribution of Dengue virus serotype(s) in the state of Manipur – a small state situated in the northeastern region of the Indian subcontinent was carried out at Viral Research & Diagnostic Laboratory (VRDL), Department of Microbiology, Regional Institute of Medical Sciences (RIMS), Imphal which is a tertiary care hospital.Materials & Methods:A total of 914 blood samples from clinically dengue-suspected patients were screened for the presence of Dengue infection by adopting the ELISA (IgM) technique during the period from 01/06/2022 to 02/12/2022. Further, anti-Dengue IgM antibody-positive samples having high Optical Density (OD) value(s) were selected and subjected to RT PCR to determine the serotype(s) of the Dengue virus.Results:Of the 914 blood samples examined for the presence of Dengue infection, 111 (12.14%) were found positive for anti- Dengue IgM antibody indicating acute infection of Dengue virus.Of the positive patients, there were 56 (50.45%) males and 55 (49.54%) females.Predominant clinical features observed among the Dengue-confirmed patients included – fever (74%), headache (19%), arthralgia / joint pain (9%), myalgia (6%) and vomiting (6%) respectively.The study revealed that while the circulation of three (03) Dengue virus serotypes, namely DENV – 1, DENV – 2 & DENV – 3 were observed in the Tengnoupal district,the circulation of two Dengue virus serotypes i.e., DENV – 1 & DENV – 2 was evident in Imphal West & Bishnupur districts respectively.The present study also reveals the occurrence of Dengue virus serotype – 1 (DENV - 1) in Churachandpur district. Conclusion:The present study reveals the circulation/distribution of three Dengue virus serotypes namely, DENV – 1, DENV – 2 and DENV – 3 among the studied samples.en_US
dc.identifier.affiliationsLaitonjam Anand Singh, Scientist C Virus Research Diagnostic Laboratory VRDL, Department of Microbiology, Regional Institute of Medical Sciences, Imphal, Manipur , India.en_US
dc.identifier.affiliationsThingujam Suson, Scientist B Virus Research Diagnostic Laboratory VRDL, Department Of Microbiology, Regional Institute Of Medical Sciences, Imphal, Manipur , India.en_US
dc.identifier.affiliationsChongtham Geeta Chanu, Research Assistant Virus Research Diagnostic Laboratory VRDL, Department Of Microbiology, Regional Institute of Medical Sciences, Imphal, Manipur , India.en_US
dc.identifier.affiliationsKhuraijam Ranjana Devi, Principal Investigator VRDL and Professor Head, Department Of Microbiology , Regional Institute of Medical Sciences, Imphal, Manipur, India.en_US
dc.identifier.affiliationsHeigrujam Rebachandra Singh, CoPrincipal Investigator VRDL Professor, Department Of Microbiology , Regional Institute of Medical Sciences, Imphal, Manipur, India.en_US
dc.identifier.citationAnand Singh L, Suson T, Geeta Chanu C, Ranjana Devi K, Rebachandra Singh H. Dengue Serotypes In Manipur –Findings From A Retrospective Analytical Study In A Tertiary Care Hospital. International Journal of Medical Research & Review . 2023 Nov; 11(6): 136-145en_US
dc.identifier.issn2320-8686
dc.identifier.issn2321-127X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/231050
dc.languageenen_US
dc.publisherSiddharth Health Research and Social Welfare Societyen_US
dc.relation.issuenumber6en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.17511/ijmrr.2023.i06.02en_US
dc.subjectDengue virusen_US
dc.subjectDengue IgM ELISAen_US
dc.subjectDengue serotype (RT PCR)en_US
dc.titleDengue Serotypes In Manipur –Findings From A Retrospective Analytical Study In A Tertiary Care Hospitalen_US
dc.typeJournal Articleen_US
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