Secondary mania caused by olfactory groove meningioma: A case report

Simple item page
dc.contributor.authorKim, Gen_US
dc.contributor.authorKu, Hen_US
dc.contributor.authorKu, B.en_US
dc.date.accessioned2025-08-13T09:59:09Z
dc.date.available2025-08-13T09:59:09Z
dc.date.issued2025-04
dc.description.abstractThe major clinical manifestations of orbitofrontal cortex lesions include disinhibition, perseveration and obsessive朿ompulsive and antisocial behaviours. Some patients with orbitofrontal cortex lesion can show mood elevation. We report a 69-year-old female who presented with manic and inappropriate emotional responses caused by a large olfactory groove meningioma. Magnetic resonance imaging showed a large, extra-axial mass with homogenous enhancement in the olfactory groove, compressing the orbitofrontal cortex. She showed no focal or lateralising neurological signs. We did standardized neuropsychological batteries, including the Young Mania rating scale to evaluate her manic symptoms. After removal of the tumour, her manic symptoms and abnormal behaviours gradually disappeared. These findings suggest that her manic symptoms might have resulted from compression of the orbitofrontal cortex due to the olfactory groove meningioma. Clinicians must have an index of suspicion for organic brain lesion compressing the orbitofrontal area when a patient without a history of psychiatric disease develops progressive manic symptoms.en_US
dc.identifier.affiliationsDepartment of Neurology Gounbom Neurology Clinic, Gwangmyung, Gyeonggi-do, South Koreaen_US
dc.identifier.affiliationsDepartment of Neurology Institute for Cognitive Intervention, International St. Mary抯 Hospital, Catholic Kwandong University College of Medicine, Incheon, South Korea.en_US
dc.identifier.citationKim G, Ku H, Ku B.. Secondary mania caused by olfactory groove meningioma: A case report. National Medical Journal of India. 2025 Apr; 38(2): 96-99en_US
dc.identifier.issn0970-258X
dc.identifier.issn2583-150X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/252860
dc.languageenen_US
dc.publisherAll India Institute of Medical Sciencesen_US
dc.relation.issuenumber2en_US
dc.relation.volume38en_US
dc.source.urihttps://doi.org/10.25259/NMJI_170_2023en_US
dc.titleSecondary mania caused by olfactory groove meningioma: A case reporten_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
nmji2025v38n2p96.pdf
Size:
2.27 MB
Format:
Adobe Portable Document Format
Download
Collections
National Medical Journal of India