Secondary mania caused by olfactory groove meningioma: A case report
No Thumbnail Available
Date
2025-04
Journal Title
Journal ISSN
Volume Title
Publisher
All India Institute of Medical Sciences
Abstract
The major clinical manifestations of orbitofrontal cortex lesions include disinhibition, perseveration and obsessive朿ompulsive and antisocial behaviours. Some patients with orbitofrontal cortex lesion can show mood elevation. We report a 69-year-old female who presented with manic and inappropriate emotional responses caused by a large olfactory groove meningioma. Magnetic resonance imaging showed a large, extra-axial mass with homogenous enhancement in the olfactory groove, compressing the orbitofrontal cortex. She showed no focal or lateralising neurological signs. We did standardized neuropsychological batteries, including the Young Mania rating scale to evaluate her manic symptoms. After removal of the tumour, her manic symptoms and abnormal behaviours gradually disappeared. These findings suggest that her manic symptoms might have resulted from compression of the orbitofrontal cortex due to the olfactory groove meningioma. Clinicians must have an index of suspicion for organic brain lesion compressing the orbitofrontal area when a patient without a history of psychiatric disease develops progressive manic symptoms.
Description
Keywords
Citation
Kim G, Ku H, Ku B.. Secondary mania caused by olfactory groove meningioma: A case report. National Medical Journal of India. 2025 Apr; 38(2): 96-99