A clinicopathological study of multidrug therapy in borderline tuberculoid leprosy.

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dc.contributor.authorKar, P Ken_US
dc.contributor.authorArora, P Nen_US
dc.contributor.authorRamasastry, C Ven_US
dc.contributor.authorDhaka, R Sen_US
dc.date.accessioned1994-10-01en_US
dc.date.accessioned2009-05-31T12:49:56Z
dc.date.available1994-10-01en_US
dc.date.available2009-05-31T12:49:56Z
dc.date.issued1994-10-01en_US
dc.description.abstractA study was undertaken to evaluate the efficacy of multidrug therapy as per WHO recommendation in 50 fresh cases (46 males and 4 females) suffering from borderline tuberculoid leprosy. All were given multidrug therapy consisting of rifampicin 600 mg once a month and dapsone 100 mg daily for 6 months. At the end of 6 months all were evaluated clinically and histopathological examinations of the lesions were studied. The lesions were still active in 60% of patients clinically; 32% cases receiving multidrug therapy had shown marked improvement. Histologically lymphocytic infiltration in skin still persisted in all the slides examined and nerve infiltration was still present in 68% of cases at the end of 6 months after receiving multidrug therapy. The study shows that treatment with multidrug regimen for 6 months may not be sufficient to treat borderline tuberculoid leprosy cases.en_US
dc.description.affiliationDepartment of Dermatology, STD and Leprosy, Command Hospital (SC), Pune.en_US
dc.identifier.citationKar PK, Arora PN, Ramasastry CV, Dhaka RS. A clinicopathological study of multidrug therapy in borderline tuberculoid leprosy. Journal of the Indian Medical Association. 1994 Oct; 92(10): 336-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/101374
dc.language.isoengen_US
dc.source.urihttps://www.jimaonline.org.in/en_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshDapsone --therapeutic useen_US
dc.subject.meshDrug Therapy, Combinationen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLeprosy, Borderline --drug therapyen_US
dc.subject.meshLeprosy, Tuberculoid --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRifampin --therapeutic useen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleA clinicopathological study of multidrug therapy in borderline tuberculoid leprosy.en_US
dc.typeJournal Articleen_US
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