DEVELOPMENT, FORMULATION, AND EVALUATION OF ALOE VERA TOOTH GEL: AN ANTIMICROBIAL STUDY

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dc.contributor.authorRUDRA, ANANDAMOYen_US
dc.contributor.authorSHOEB, ABUen_US
dc.date.accessioned2024-09-24T08:25:10Z
dc.date.available2024-09-24T08:25:10Z
dc.date.issued2023-10
dc.description.abstractObjective: The purpose of the current study was to develop and formulate tooth gel using Aloe vera leaf extract and evaluate. The experiment was designed to provide scientific proof of the antimicrobial activity of Aloe vera (Aloe barbadensis Mill) in tooth gel formulation against bacteria Staphylococcus aureus which causes infections associated with dental caries.Methods: Transparent Aloe vera gel extract was consistently blended for five minutes at 1000 Rotations Per Minute (RPM). Carbopol 940 and Carboxy Methyl Cellulose (CMC) were used as excipients in the formulation of Aloe vera tooth gel.Results: The formulated Aloe vera tooth gel was evaluated by physical examination such as color (yellowish green), good homogeneity and smoothness. pH and viscosity of developed tooth gel preparation were found to be 7.9 and 4.9 Pa. S respectively. The developed Aloe vera tooth gel showed considerable effectiveness with a Zone of Inhibition (ZOI) of 0.022 m, according to an antimicrobial study against Staphylococcus aureus. A comparison between formulated gel and marketed products (Colgate Natural Extract Aloe vera, Himalaya Herbal Active Fresh, Dabur Red) was also carried out.Conclusion: The formulated herbal tooth gel exhibited antimicrobial activity against gram-positive bacteria Staphylococcus aureus. The developed formulation (F4) with the ZOI of 0.022 m could be comparable with the marketed product.en_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Bengal School of Technology, Sugandha, Delhi Road, Hooghly-712102, West Bengal, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Bengal School of Technology, Sugandha, Delhi Road, Hooghly-712102, West Bengal, Indiaen_US
dc.identifier.citationRUDRA ANANDAMOY, SHOEB ABU . DEVELOPMENT, FORMULATION, AND EVALUATION OF ALOE VERA TOOTH GEL: AN ANTIMICROBIAL STUDY . International Journal of Pharmacy and Pharmaceutical Sciences . 2023 Oct; 15(10): 6-12en_US
dc.identifier.issn0975-1491
dc.identifier.issn2656-0097
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/231265
dc.languageenen_US
dc.publisherInnovare Academic Sciences Pvt. Ltd.en_US
dc.relation.issuenumber10en_US
dc.relation.volume15en_US
dc.source.urihttps://doi.org/10.22159/ijpps.2023v15i10.48765en_US
dc.subjectAloe veraen_US
dc.subjectTooth gelen_US
dc.subjectAttenuated total reflectance (ATR)en_US
dc.subjectAntimicrobial studyen_US
dc.subjectStaphylococcus aureusen_US
dc.subjectDental cariesen_US
dc.titleDEVELOPMENT, FORMULATION, AND EVALUATION OF ALOE VERA TOOTH GEL: AN ANTIMICROBIAL STUDYen_US
dc.typeJournal Articleen_US
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