Phytochemical Screening and Biological Studies of the Leaves of Microtrichia perotitii DC (Asteraceae).
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Date
2011-07
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Abstract
The Butanolic soluble fraction (F3) of the leaves of Microtrichia perotitii DC was
evaluated for its analgesic and anti-inflammatory effects on laboratory animals. The
results of analgesic studies was dose dependent and showed significant inhibition of
writhings in rats while those of the anti-inflammatory studies was dose independent and
the values obtained were significantly different from the control (ketoprofene) at
P<0.5,P<0.01 and P≤0.001 under the student’s t-test. There were remarkable
reductions of paw edema in the mice. The results of the biological studies expose the
local usage of the leaves for the treatment of pains and inflammation. The
phytochemical screening of the leaves revealed the presence of Saponins, Flavonones,
Alkaloids and Tanins.
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Keywords
Butanolic soluble, Microtrichia perotitii, analgesic, anti-inflammatory, phytochemical, writhings
Citation
Abdullahi M N, Ibrahim H, Ilyas N. Phytochemical Screening and Biological Studies of the Leaves of Microtrichia perotitii DC (Asteraceae). European Journal of Medicinal Plants. 2011 Jul-Sept; 1(3): 88-97.