Evaluation of analgesic activity of Emblica officinalis in albino rats.

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dc.contributor.authorGoel, Bhomik
dc.contributor.authorPathak, Nishant
dc.contributor.authorNim, Dwividendra Kumar
dc.contributor.authorSingh, Sanjay Kumar
dc.contributor.authorDixit, Rakesh Kumar
dc.contributor.authorChaurasia, Rakesh
dc.date.accessioned2014-12-18T04:37:45Z
dc.date.available2014-12-18T04:37:45Z
dc.date.issued2014-03
dc.description.abstractBackground: Amla is one of the most often used herbs in indigenous medicine, whose all parts including fruit, seed, leaves, root, bark, and fl owers are used in various Ayurvedic/Unani medicines. However, studies to establish analgesic potential of amla were limited, so the purpose of the present study was to evaluate analgesic activity of amla, if it possesses any. Methods: Albino rats were divided randomly in three groups of six rats each. Group 1 (control) received distilled water orally, Group 2 (test) received Emblica offi cinalis extract in dose of 600 mg/kg orally and Group 3 (standard) received Pentazocine in dose 10 mg/kg intraperitoneally. Results: Emblica offi cinalis extract did not produced statistically signifi cant (p>0.05) analgesia when compared with the control group in hot plate latency, but produced a statistically signifi cant reduction in 6% NaCl induced abdominal writhing (p<0.05). Conclusions: Since the plant extract signifi cantly reduced the number of writhes in abdominal writhing model, but do not increase hot plate latency, the commercially available crude extract of Emblica offi cinalis exhibit analgesic activity involving peripheral mechanisms.en_US
dc.identifier.citationGoel Bhomik, Pathak Nishant, Nim Dwividendra Kumar, Singh Sanjay Kumar, Dixit Rakesh Kumar, Chaurasia Rakesh. Evaluation of analgesic activity of Emblica officinalis in albino rats. International Journal of Basic & Clinical Pharmacology. 2014 Mar-Apr; 3(2): 365-368.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/154023
dc.language.isoenen_US
dc.source.urihttps://www.ijbcp.com/?mno=151590en_US
dc.subjectEmblica officinalisen_US
dc.subjectAmlaen_US
dc.subjectAnti-nociceptiveen_US
dc.subjectPainen_US
dc.subjectAnalgesicen_US
dc.subjectHot plate methoden_US
dc.titleEvaluation of analgesic activity of Emblica officinalis in albino rats.en_US
dc.typeArticleen_US
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