A comparison of the clinical efficacy of ranitidine and sucralfate in reflux esophagitis.

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dc.contributor.authorChopra, B Ken_US
dc.contributor.authorKazal, H Len_US
dc.contributor.authorMittal, P Ken_US
dc.contributor.authorSibia, S Sen_US
dc.date.accessioned1992-07-01en_US
dc.date.accessioned2009-05-30T21:27:40Z
dc.date.available1992-07-01en_US
dc.date.available2009-05-30T21:27:40Z
dc.date.issued1992-07-01en_US
dc.description.abstractA total of 40 patients with endoscopically proved reflux esophagitis were treated in a randomised study. Treatment was given for six weeks and consisted of daily doses of either 1 gm sucralfate four times a day or one, 150 mg ranitidine tablet twice daily. Twenty patients received each drug. Clinical evaluation was done weekly and endoscopic evaluation after six weeks. Forty percent patients on ranitidine and 50% patients on sucralfate became asymptomatic at six weeks. Fifty percent patients on ranitidine and 60% patients on sucralfate were endoscopically healed. The results did not show any difference in the effect of ranitidine and sucralfate treatment (p > 0.05). Overall tolerance and compliance in the two forms of treatment was good. Though ranitidine has a more convenient dose schedule and is more cost effective, sucralfate needs further clinical trials.en_US
dc.description.affiliationDepartment of Medicine, Govt. Medical College, Rajendra Hospital, Patiala.en_US
dc.identifier.citationChopra BK, Kazal HL, Mittal PK, Sibia SS. A comparison of the clinical efficacy of ranitidine and sucralfate in reflux esophagitis. Journal of the Association of Physicians of India. 1992 Jul; 40(7): 439-41en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/88640
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshEsophagitis, Peptic --drug therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPatient Complianceen_US
dc.subject.meshRanitidine --therapeutic useen_US
dc.subject.meshSucralfate --therapeutic useen_US
dc.titleA comparison of the clinical efficacy of ranitidine and sucralfate in reflux esophagitis.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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