Development of natural gum based glipizide mucoadhesive microsphere.

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dc.contributor.authorMamun, Md. Abdur Rouf Al
dc.contributor.authorBagchi, Monisha
dc.contributor.authorAmin, Md. Lutful
dc.contributor.authorSutradhar, Kumar Bishwajit
dc.contributor.authorHuda, Naz Hasan
dc.date.accessioned2014-06-13T06:19:59Z
dc.date.available2014-06-13T06:19:59Z
dc.date.issued2014-01
dc.description.abstractThe objective of this study was to develop glipizide microsphere with natural gums. Guar gum and xanthan gum were used separately in different ratios as natural polymers. The microspheres were prepared by orifice ionic gelation method and they were characterized by scanning electron microscopy and particle size analysis. Among six formulations, microspheres of four formulations (F1-F4) were discrete, sphrerical and free flowing. There was an inverse relationship found between the amount of gum and surface smoothness in case of guar gum-containing microspheres while a forward relationship was found between amount of gum and surface smoothness in case of the microspheres containing xanthan gum. The size of the particles increased with increasing amounts of gum. It can be concluded that guar gum and natural gum at a ratio of 1:0.25 and 1:0.5 can be ideal for formulating natural gum based glipizide mucoadhesive microsphere.en_US
dc.identifier.citationMamun Md Abdur Rouf Al, Bagchi Monisha, Amin Md Lutful, Sutradhar Kumar Bishwajit, Huda Naz Hasan. Development of natural gum based glipizide mucoadhesive microsphere. Journal of Applied Pharmaceutical Science. 2014 Jan; 4(1): 66-69.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/151985
dc.language.isoenen_US
dc.source.urihttps://www.japsonline.com/counter.php?aid=1160en_US
dc.subjectGlipizideen_US
dc.subjectmucoadhesive microsphereen_US
dc.subjectguar gumen_US
dc.subjectxanthan gumen_US
dc.subjectionic gelation methoden_US
dc.titleDevelopment of natural gum based glipizide mucoadhesive microsphere.en_US
dc.typeArticleen_US
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