The efficacy of Thai capsaicin in the treatment of primary detrusor instability and hypersensitive bladder.

dc.contributor.authorNonthasood, Bunjerd
dc.contributor.authorSoontrapa, Suchai
dc.contributor.authorAmornvesukit, Teerapon
dc.contributor.authorTappayuthpijarn, Pimolvan
dc.contributor.authorSuebnukanwattana, Thitiporn
dc.date.accessioned2012-03-30T05:44:19Z
dc.date.available2012-03-30T05:44:19Z
dc.date.issued2001-07
dc.description.abstractOur an objective was to study the efficacy of Capsaicin extracted from Capsaicin frutescen in treating the patients with hypersensitive bladder and primary detrusor instability. Eleven patients, 3 males and 8 females, with average age of 60.3ฑ14.3 years were treated by intravesical instillation 1 mM/L Capsaicin in 30% ethanol in an amount half of the bladder capacity for 30 minutes after instillation 2% xylocaine without adrenaline for 15 minutes three out of the 11 patients who could not tolerate the pain by this method were anesthesized with regional or general anesthesia. The results were as follow :- 1. Clinical symptoms were improved significantly, i e. the frequency was reduced from day : night = 19.45ฑ17.99 : 7.09ฑ6.30 to 12.00ฑ8.91 : 4.09ฑ3.8 at p < 0.05 and leakage almost disappeared. 2. Maximal bladder capacity increased from 197.45ฑ156.06 ml to 323.45ฑ129.46 ml which was statistically significant (p=0.009). 3. Detrusor pressure at maximal bladder capacity increased from 32.63ฑ22.76 cmH2O to 36.63ฑ19.21 cmH2O but was not statistically significant (P=0.823). 4. Voiding pressure nonsignificantly increased from 47.1ฑ6.4 cmH2O to 48.1ฑ6.6 cmH2O (p=0.959). The adverse effects found were burning pain at suprapubic area, sweating and hematuria.en_US
dc.identifier.citationNonthasood Bunjerd, Soontrapa Suchai, Amornvesukit Teerapon, Tappayuthpijarn Pimolvan, Suebnukanwattana Thitiporn. The efficacy of Thai capsaicin in the treatment of primary detrusor instability and hypersensitive bladder. Siriraj Medical Journal, 2001 Jul; 53(7): 406-413.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/137399
dc.language.isoenen_US
dc.source.urihttps://www.sirirajmedj.com/content_download.php?content_id=901en_US
dc.subjectCapsaicinen_US
dc.subjectDetrusor instabilityen_US
dc.subjectHypersensitive bladderen_US
dc.titleThe efficacy of Thai capsaicin in the treatment of primary detrusor instability and hypersensitive bladder.en_US
dc.typeArticleen_US
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