Primary bone solitary B-cell lymphoblastic lymphoma aberrant expression Fli-1 and ERG: A case report

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dc.contributor.authorChen, Hen_US
dc.contributor.authorLi, JSen_US
dc.contributor.authorHuang, Yen_US
dc.date.accessioned2025-06-19T05:55:12Z
dc.date.available2025-06-19T05:55:12Z
dc.date.issued2025-03
dc.description.abstractPrimary non?Hodgkin bone lymphoma is a rare disease, and within this category, B?cell lymphoblastic lymphoma (B?LBL) is an even rare clinical entity that has only been reported in small case series or individual case reports. B?LBL can mimic Ewing’s sarcoma both clinically and histologically, leading to misdiagnosis. We present a case of primary B?LBL of the bone in a 7?year?old girl. The tumor cells are uniform and small with a diffuse and infiltrative growth pattern similar to EWS. Immunohistochemical results are positive for CD99, Fli?1, ERG, TDT, PAX5, and CD79?, but negative for leukocyte common antigen, CD3, CD20, and NKX2.2. No other lesions are found on positron emission tomography/ computed tomography imaging. Finally, primary solitary bone B?LBL of the right tibia was diagnosed.en_US
dc.identifier.affiliationsDepartment of Pathology, Yichun People’s Hospital, Yichun, Jiangxi Provinceen_US
dc.identifier.affiliationsDepartment of Pathology, Yichun People’s Hospital, Yichun, Jiangxi Provinceen_US
dc.identifier.affiliationsDepartment of Pathology, 81st Group Army Hospital of PLA, Zhang Jiakou, Hebei Province, P. R. Chinaen_US
dc.identifier.citationChen H, Li JS, Huang Y. Primary bone solitary B-cell lymphoblastic lymphoma aberrant expression Fli-1 and ERG: A case report. Indian Journal of Pathology & Microbiology. 2025 Mar; 68(1): 219-221en_US
dc.identifier.issn0377-4929
dc.identifier.issn0974-5130
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/249959
dc.languageenen_US
dc.publisherWolters Kluwer - Medknowen_US
dc.relation.issuenumber1en_US
dc.relation.volume68en_US
dc.source.urihttps://doi.org/10.4103/ijpm.ijpm_619_23en_US
dc.subjectB?cells lymphoblastic lymphomaen_US
dc.subjectEwing’s sarcomaen_US
dc.subjectERGen_US
dc.subjectFli?1en_US
dc.subjectprimary bone lymphomaen_US
dc.titlePrimary bone solitary B-cell lymphoblastic lymphoma aberrant expression Fli-1 and ERG: A case reporten_US
dc.typeJournal Articleen_US
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