White Spot Syndrome Virus infection in Penaeus monodon is facilitated by housekeeping molecules.

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dc.contributor.authorBiradar, Vinayak
dc.contributor.authorNarwade, Santosh
dc.contributor.authorPaingankar, Mandar
dc.contributor.authorDeobagkar, Deepti
dc.date.accessioned2015-08-14T09:43:13Z
dc.date.available2015-08-14T09:43:13Z
dc.date.issued2013-12
dc.description.abstractWhite Spot Syndrome Virus (WSSV) is a major pathogen in shrimp aquaculture, and its rampant spread has resulted in great economic loss. Identification of host cellular proteins interacting with WSSV will help in unravelling the repertoire of host proteins involved in WSSV infection. In this study, we have employed one-dimensional and twodimension virus overlay protein binding assay (VOPBA) followed by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) to identify the host proteins of Penaeus monodon that could interact with WSSV. The VOPBA results suggest that WSSV interacted with housekeeping proteins such as heat shock protein 70, ATP synthase subunit β, phosphopyruvate hydratase, allergen Pen m 2, glyceraldehyde-3-phosphate dehydrogenase, sarcoplasmic calcium-binding protein, actin and 14-3-3-like protein. Our findings suggest that WSSV exploits an array of housekeeping proteins for its transmission and propagation in P. monodon.en_US
dc.identifier.citationBiradar Vinayak, Narwade Santosh, Paingankar Mandar, Deobagkar Deepti. White Spot Syndrome Virus infection in Penaeus monodon is facilitated by housekeeping molecules. Journal of Biosciences. 2013 Dec; 38(5): 917-924.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/161881
dc.language.isoenen_US
dc.source.urihttps://www.ias.ac.in/jbiosci/dec2013/917.pdfen_US
dc.subjectATP synthase β subuniten_US
dc.subjectHSP70en_US
dc.subjectvirus–host interactionen_US
dc.subjectvirus overlay protein binding assayen_US
dc.titleWhite Spot Syndrome Virus infection in Penaeus monodon is facilitated by housekeeping molecules.en_US
dc.typeArticleen_US
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