Drug utilization pattern of antiepileptic agents among pediatric epilepsy at tertiary care teaching hospital of Gujarat: a cross sectional study

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dc.contributor.authorDave, Hirenkumar H.en_US
dc.contributor.authorTrivedi, Niyati A.en_US
dc.date.accessioned2020-04-23T07:51:10Z
dc.date.available2020-04-23T07:51:10Z
dc.date.issued2018-08
dc.description.abstractBackground: Epilepsy is one of the most common neurological disorders characterized by recurrent episodic paroxysmal involuntary clinical events associated with abnormal electrical activity from the neurons. Without the knowledge of how drugs are being prescribed and used, it is difficult to initiate discussion on rationale drug use and to suggest measures to change prescribing habits for the better management. Present study was performed with an aim to study the utilization pattern of anti-epileptic drugs (AEDs) for the paediatric patients suffering from various forms of epileptic seizures.Methods: The present cross-sectional study was conducted at the epilepsy clinic of Department of Paediatrics, Tertiary Care Teaching Hospital of Gujarat, on patients diagnosed to have epilepsy July 2014 to October 2014. Hundred Paediatric patients of either gender diagnosed to had epilepsy and taking treatment from pediatric epilepsy clinic OPD, S.S.G. Hospital, and Baroda. Patient抯 detailed medical history, demographic details and other required information was recorded on a prestructured data entry form.Results: Out of 100. GTCS was found to be the most common (55%) form of epilepsy among pediatric patients and Carbamazepine was the most commonly prescribed (41%) AED followed by sodium valproate (38%). 71% patients were prescribed monotherapy. Carbamazepine +Clobazam was the most commonly (7%) used combination.Conclusions: Use of appropriate AEDs in the majority of patients as per WHO guidelines, has decreased number of ADRs in this study.en_US
dc.identifier.affiliationsDepartment of Pharmacology, Zydus Medical College and Hospital, Dahod, Gujarat, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, Government Medical College, Vadodara, Gujarat, Indiaen_US
dc.identifier.citationDave Hirenkumar H., Trivedi Niyati A.. Drug utilization pattern of antiepileptic agents among pediatric epilepsy at tertiary care teaching hospital of Gujarat: a cross sectional study. International Journal of Basic & Clinical Pharmacology. 2018 Aug; 7(8): 1606-1611en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/199802
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber8en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2319-2003.ijbcp20183031en_US
dc.subjectCarbamazepineen_US
dc.subjectCross-sectional studyen_US
dc.subjectEpilepsyen_US
dc.subjectSeizuresen_US
dc.titleDrug utilization pattern of antiepileptic agents among pediatric epilepsy at tertiary care teaching hospital of Gujarat: a cross sectional studyen_US
dc.typeJournal Articleen_US
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