Effect of vitamin D deficiency on electrocardiogram of rats.

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1995-01-01
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Abstract
Electrocardiograms (ECGs) were studied in rats fed vitamin D deficient diet for 12 weeks. The results indicated significant shortening of QT interval of ECG. Other intervals were normal when compared with age matched control rats. Heart/body weight ratio was significantly increased in vitamin D deficient group, which is an index of hypertrophy, with increased collagen fiber in the histology of the myocardium, inspite of normal serum calcium level. The results suggested a direct role of vitamin D in the regulation of cardiac functions.
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Sood S, Reghunandanan R, Reghunandanan V, Gopinathan K, Sood AK. Effect of vitamin D deficiency on electrocardiogram of rats. Indian Journal of Experimental Biology. 1995 Jan; 33(1): 61-3