Efficacy and Cardiovascular Safety of Topical Timolol, Brimonidine & Latanoprost in Newly Diagnosed Patients of Open Angle Glaucoma.

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dc.contributor.authorKapoor, Kiran
dc.contributor.authorKhajuria, Vijay
dc.contributor.authorKapoor, B
dc.contributor.authorGupta, Satish
dc.date.accessioned2016-02-10T04:03:05Z
dc.date.available2016-02-10T04:03:05Z
dc.date.issued2013-01
dc.description.abstractThe present study was conducted in chronic open angle glaucoma patients to evaluate their efficacy in reducing IOP and their cardiovascular safety. 48 newly diagnosed patients of glaucoma completed the trial. Patients were divided into three groups and received medications in form of topical instillations. Group I (Timolol 0.5% twice a day), Group II (Brimonidine Tatrate 0.2% twice a day) & Group III (Latanoprost 0.005% once a day) for 12 weeks. All the three medications, significantly decreased IOP (P<0.05), however, Latanoprost caused maximum decrease in IOP, followed by Brimonidine and Timolol. Visual Acquity was not affected by any of the medication. Pulse Rate and PR Interval were decreased in Timolol group significantly (P < 0.001) while Brimonidine and Latanoprost did not alter Pulse Rate. Blood Pressure was not affected by either of medication except Brimonidine which caused reduction in systolic Blood Pressure at 12 weeks. The results of present study demonstrates superiority of Latanoprost over Timolol and Brimonidine as it lacked effect on Pulse Rate, Blood Pressure and HR, besides being more efficacious.en_US
dc.identifier.citationKapoor Kiran, Khajuria Vijay, Kapoor B, Gupta Satish. Efficacy and Cardiovascular Safety f Topical Timolol, Brimonidine & Latanoprost in Newly Diagnosed Patients of Open Angle Glaucoma. JK Science Journal of Medical Education and Research. 2013 Jan-Mar;15(1): 15-18.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/172235
dc.language.isoenen_US
dc.source.urihttps://www.jkscience.org/archives/volume145/Original_Article2.pdfen_US
dc.subjectGlaucomaen_US
dc.subjectLatanoprosten_US
dc.subjectBrimonidineen_US
dc.subjectTimololen_US
dc.subjectIOPen_US
dc.subjectPulse Rateen_US
dc.subjectHRen_US
dc.subjectPR-Intervalen_US
dc.titleEfficacy and Cardiovascular Safety of Topical Timolol, Brimonidine & Latanoprost in Newly Diagnosed Patients of Open Angle Glaucoma.en_US
dc.typeArticleen_US
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