In vivo antioxidant and lipid peroxidation effect of methanolic extract of tuberous root of Ipomoea digitata (Linn) in rat fed with high fat diet.

Simple item page
dc.contributor.authorAlagumanivasagam, G
dc.contributor.authorMuthu, A Kottai
dc.contributor.authorKumar, D Satheesh
dc.contributor.authorSuresh, K
dc.contributor.authorManavalan, R
dc.date.accessioned2015-04-21T05:59:44Z
dc.date.available2015-04-21T05:59:44Z
dc.date.issued2010-08
dc.description.abstractThe study was carried out to determine the in vivo antioxidant and lipid peroxidation effect of methanolic extract of tuberous root of Ipomoea digitata (Linn). High fat diet rats showed significantly (P<0.001) reduced the levels of tissues enzymatic antioxidant and enhanced the level of non enzymatic antioxidant (Glutathione). The level of TBARS are elevated in HFD rats (group II) when compared with control group. High fat diet induces the oxidative stress in cell by producing reactive oxygen species. Administration of methanolic extract of Ipomoea digitata in high fat diet rats were showed increased the levels of antioxidant Enzymes such as Superoxide dismutase (SOD), Catalase (CAT), Glutathione peroxidase (GPx), Glutathione reductase (GR) and reduced the level of non enzymatic antioxidant Glutathione (GSH) when compared with HFD rats (Group II). The methanolic extract Ipomoea digitata in high fat diet rats were found lowered the concentration of TBARS when compared with HFD rats. Based on the results, we concluded that the methanolic extract of Ipomoea digitata is a significant source of natural antioxidant, which might be helpful in preventing the progress of various oxidative stresses.en_US
dc.identifier.citationAlagumanivasagam G, Muthu A Kottai, Kumar D Satheesh, Suresh K, Manavalan R. In vivo antioxidant and lipid peroxidation effect of methanolic extract of tuberous root of Ipomoea digitata (Linn) in rat fed with high fat diet. International Journal of Applied Biology and Pharmaceutical Technology. 2010 Aug-Oct; 1(2): 214-220.en_US
dc.identifier.issn0976-4550
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/157686
dc.language.isoenen_US
dc.source.urihttps://www.ijabpt.com/pdf/533-Kottai%20Muthu.pdfen_US
dc.subjectHigh fat dieten_US
dc.subjectIpomoea digitataen_US
dc.subjectAntioxidant activityen_US
dc.subjectratsen_US
dc.titleIn vivo antioxidant and lipid peroxidation effect of methanolic extract of tuberous root of Ipomoea digitata (Linn) in rat fed with high fat diet.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijabpt2010v1n2p214.pdf
Size:
179.99 KB
Format:
Adobe Portable Document Format
Description:
Journal article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
International Journal of Applied Biology and Pharmaceutical Technology