Thyroid Spectrum Disease in Patients with Type 2 Diabetes Mellitus

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dc.contributor.authorShah, Bhagwan Babuen_US
dc.contributor.authorDaha, Sunil Kumaren_US
dc.contributor.authorBK, Mukeshen_US
dc.contributor.authorLamichhane, Binitaen_US
dc.date.accessioned2025-05-09T11:04:42Z
dc.date.available2025-05-09T11:04:42Z
dc.date.issued2024-08
dc.description.abstractIntroduction: There is a complex underlying relation between diabetes mellitus and thyroid dysfunction. This is attributable to an array of complex intertwining biochemical, genetic and hormonal malfunctions mirroring this patho-physiological association. Autoimmunity has been implicated to be the major cause of thyroid-dysfunction associated diabetes mellitus. Hence, the current study aimed to establish the prevalence of thyroid dysfunction in type 2 diabetes mellitus. Materials and Methods: The current study was carried out on 100 type 2 diabetes mellitus patients attending department of Internal Medicine, National Medical College, Birgunj from July 2018 to July 2019. After obtaining informed consent, socio-demographic, clinical and anthropometric data was collected as per a structured proforma. Also, blood was collected from each patient to obtain fasting blood sugar, post prandial blood sugar, Glycated hemoglobin, triiodothyronine, and thyroxine and thyrotropin levels. Statistical analysis was done as per standard protocol. Result: The mean Body Mass Index of our patients was 24.88 (SD�26) kg/m2 and body mass index was significantly associated with thyroid dysfunction (p value=.043).Thyroid dysfunction was present in 31% of patients. Also, thyroid dysfunction was significantly associated with fasting blood sugar, post prandial blood sugar and HbA1c levels. Conclusion: Thyroid dysfunction has a high prevalence in type 2 diabetes mellitus. Hence, all type 2 diabetes mellitus must undergo screening for thyroid dysfunction for optimal patient management.en_US
dc.identifier.affiliationsDepartment of Medicine, National Medical College, Birgunjen_US
dc.identifier.affiliationsDepartment of Medicine, National Medical College, Birgunjen_US
dc.identifier.affiliationsDepartment of Medicinem, National Medical College, Birgunjen_US
dc.identifier.affiliationsDepartment of Medicine, National Medical College, Birgunjen_US
dc.identifier.citationShah Bhagwan Babu, Daha Sunil Kumar, BK Mukesh, Lamichhane Binita . Thyroid Spectrum Disease in Patients with Type 2 Diabetes Mellitus. International Journal of Contemporary Medical Research. 2024 Aug; 11(8): 1-4en_US
dc.identifier.issn2393-915X
dc.identifier.issn2454-7379
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/246176
dc.languageenen_US
dc.publisherInternational Society for Contemporary Medical Researchen_US
dc.relation.issuenumber8en_US
dc.relation.volume11en_US
dc.source.urihttps://www.ijcmr.com/uploads/7/7/4/6/77464738/ijcmr_3744.pdfen_US
dc.subjectDiabetesen_US
dc.subjectThyroid spectrum Disorder.en_US
dc.titleThyroid Spectrum Disease in Patients with Type 2 Diabetes Mellitusen_US
dc.typeJournal Articleen_US
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