Thyroid Spectrum Disease in Patients with Type 2 Diabetes Mellitus
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Date
2024-08
Journal Title
Journal ISSN
Volume Title
Publisher
International Society for Contemporary Medical Research
Abstract
Introduction: There is a complex underlying relation between diabetes mellitus and thyroid dysfunction. This is attributable to an array of complex intertwining biochemical, genetic and hormonal malfunctions mirroring this patho-physiological association. Autoimmunity has been implicated to be the major cause of thyroid-dysfunction associated diabetes mellitus. Hence, the current study aimed to establish the prevalence of thyroid dysfunction in type 2 diabetes mellitus. Materials and Methods: The current study was carried out on 100 type 2 diabetes mellitus patients attending department of Internal Medicine, National Medical College, Birgunj from July 2018 to July 2019. After obtaining informed consent, socio-demographic, clinical and anthropometric data was collected as per a structured proforma. Also, blood was collected from each patient to obtain fasting blood sugar, post prandial blood sugar, Glycated hemoglobin, triiodothyronine, and thyroxine and thyrotropin levels. Statistical analysis was done as per standard protocol. Result: The mean Body Mass Index of our patients was 24.88 (SD�26) kg/m2 and body mass index was significantly associated with thyroid dysfunction (p value=.043).Thyroid dysfunction was present in 31% of patients. Also, thyroid dysfunction was significantly associated with fasting blood sugar, post prandial blood sugar and HbA1c levels. Conclusion: Thyroid dysfunction has a high prevalence in type 2 diabetes mellitus. Hence, all type 2 diabetes mellitus must undergo screening for thyroid dysfunction for optimal patient management.
Description
Keywords
Diabetes, Thyroid spectrum Disorder.
Citation
Shah Bhagwan Babu, Daha Sunil Kumar, BK Mukesh, Lamichhane Binita . Thyroid Spectrum Disease in Patients with Type 2 Diabetes Mellitus. International Journal of Contemporary Medical Research. 2024 Aug; 11(8): 1-4