A comparative, qualitative and quantitative antimicrobial efficacies of mouthrinses containing chlorhexidine gluconate and essential oils.

dc.contributor.authorShah, H Men_US
dc.contributor.authorShah, M Nen_US
dc.contributor.authorGokani, V Nen_US
dc.contributor.authorJethal, B Sen_US
dc.date.accessioned2009-05-28T07:43:50Z
dc.date.available2009-05-28T07:43:50Z
dc.date.issued1993-07-01en_US
dc.description.abstractA project was launched to evaluate and compare antimicrobial efficacy of Hexidine and Listerine over placebo in 10 day human experimental gingivitis study. A rigid study schedule for subject compliance spanning well over 3 months was sorted out and volunteers recruited for study rinsed all the 3 assigned mouthrinses containing (a) chlorhexidine gluconate, (b) "essential oils" and (c) flavoured distilled water one after the other at certain prefixed intervals. After 10 days of assigned mouthrinse regimen, where the assigned mouthrinse was the only method practiced by the volunteers for oral hygiene, Supragingival Plaque was quantitatively and qualitatively assayed. Qualitatively supragingival plaque was assayed by Gram staining (Direct smear and Thioglycollate Broth) and growth characteristics i.e; Aerobic, Microaerophilic and Anaerobic growth was noted. Quantitatively plaque was assayed by calculating total microbial load per tooth by preparing Mafarland Nephelometer standard and Spectrophotometric analysis. It is concluded that Hexidine and Listerine exert similar antimicrobial efficacy in 10 days experimental gingivitis study. Hexidine and Listerine exert their antimicrobial influence through reduction of total Aerobes and Anaerobes reducing total microbial load per tooth by 58% and 53% respectively as compared to placebo.en_US
dc.description.affiliationDepartment of Periodontia, Govt. Dental College, Ahmedabad.en_US
dc.identifier.citationShah HM, Shah MN, Gokani VN, Jethal BS. A comparative, qualitative and quantitative antimicrobial efficacies of mouthrinses containing chlorhexidine gluconate and essential oils. Indian Journal of Dental Research. 1993 Jul-Dec; 4(3-4): 103-11en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/51585
dc.language.isoengen_US
dc.source.urihttps://www.ijdr.inen_US
dc.subject.meshAdulten_US
dc.subject.meshAnti-Bacterial Agents --pharmacologyen_US
dc.subject.meshBacteria, Aerobic --drug effectsen_US
dc.subject.meshBacteria, Anaerobic --drug effectsen_US
dc.subject.meshChlorhexidine --analogs & derivativesen_US
dc.subject.meshColony Count, Microbialen_US
dc.subject.meshDental Plaque --drug therapyen_US
dc.subject.meshDrug Combinationsen_US
dc.subject.meshDrug Evaluationen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMouthwashes --pharmacologyen_US
dc.subject.meshOils, Volatile --pharmacologyen_US
dc.subject.meshSalicylates --pharmacologyen_US
dc.subject.meshTerpenes --pharmacologyen_US
dc.subject.meshTooth --microbiologyen_US
dc.titleA comparative, qualitative and quantitative antimicrobial efficacies of mouthrinses containing chlorhexidine gluconate and essential oils.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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