A study of high-sensitivity c-reactive protein in bronchial asthma.

Simple item page
dc.contributor.authorSahoo, Ramesh Chandra
dc.contributor.authorAcharya, Preetam Rajgopal
dc.contributor.authorNoushad, T H
dc.contributor.authorAnand, R
dc.contributor.authorAcharya, Vishak K
dc.contributor.authorSahu, Kausalya R
dc.date.accessioned2012-05-30T06:33:48Z
dc.date.available2012-05-30T06:33:48Z
dc.date.issued2009-10
dc.description.abstractBackground. Relevance of C-reactive protein an acute phase reactant and a sensitive marker of low-grade systemic inflammation in bronchial asthma has not been fully studied. Objective. To evaluate the significance of high-sensitivity C-reactive protein (hs-CRP) in atopic and non-atopic asthma using an ultra sensitive assay. Methods. The levels of hs-CRP of 200 patients with bronchial asthma and 50 non-asthmatic control subjects were measured using a Latex enhanced immunoturbidimetric test. Spirometry with reversibility study, serum immunoglobulin-E (IgE) measurement and skin test for allergy was done in all the patients. Results. There was a significant increase in hs-CRP levels with age in atopic asthmatics but no such association was observed in the non-atopic asthmatics and control subjects. The hs-CRP levels were not influenced by sex in any group. Smokers in all the three groups had a significantly higher hs-CRP levels as compared to non-smokers. Patients with asthma had higher hs-CRP values as compared to controls. Patients with non-allergic asthma had higher mean hs-CRP as compared to atopic asthmatics and control subjects. Conclusions. The study suggests that there exists a certain degree of low-grade systemic inflammation in addition to the local bronchial inflammation in non-atopic asthmatics. Hence, hs-CRP may be used as a surrogate marker for the airway inflammation in non-atopic asthma patients.en_US
dc.identifier.citationSahoo Ramesh Chandra, Acharya Preetam Rajgopal, Noushad T H, Anand R, Acharya Vishak K, Sahu Kausalya R. A study of high-sensitivity c-reactive protein in bronchial asthma. The Indian Journal of Chest Diseases and Allied Sciences, 2009 Oct; 51(4): 213-216.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/138749
dc.language.isoenen_US
dc.source.urihttps://medind.nic.in/iae/t09/i4/iaet09i4p213.pdfen_US
dc.subjectC-reactive proteinen_US
dc.subjectHigh-sensitivity C-reactive proteinen_US
dc.subjectNon-atopic asthmaen_US
dc.subjectAcute phase proteinsen_US
dc.subject.meshAdult
dc.subject.meshAsthma --blood
dc.subject.meshAsthma --physiopathology
dc.subject.meshBiological Markers --blood
dc.subject.meshC-Reactive Protein --metabolism
dc.subject.meshFemale
dc.subject.meshFollow-Up Studies
dc.subject.meshForced Expiratory Volume
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshNephelometry and Turbidimetry
dc.subject.meshPrognosis
dc.subject.meshRetrospective Studies
dc.subject.meshSeverity of Illness Index
dc.subject.meshSpirometry
dc.titleA study of high-sensitivity c-reactive protein in bronchial asthma.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijcdas2009v51n4p213.pdf
Size:
34.32 KB
Format:
Adobe Portable Document Format
Description:
Journal article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Indian Journal of Chest Diseases & Allied Sciences