Central nervous system activity of the methanol extracts of Helianthus annuus seeds in mice model.

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dc.contributor.authorIslam, Rubab Tarannum
dc.contributor.authorIslam, Ahmed Tanjimul
dc.contributor.authorHossain, Mir Monir
dc.contributor.authorMazumderi, Kshor
dc.date.accessioned2015-12-14T04:54:15Z
dc.date.available2015-12-14T04:54:15Z
dc.date.issued2015
dc.description.abstractHelianthus annuus seeds contain various chemical components and evaluate different biological activities. The present study was carried out to investigate the central nervous system (CNS) activity of methanolic extract of Helianthus annuus seeds in mice model. General behaviour, antidepressant activity and anxiolytic activity was observed. The results revealed that the methanol extract of Helianthus annuus seeds at 100 and 200 mg/kg caused a significant increase in the spontaneous activity (general behavioural profile), moderate increase in anxiolytic activity (light-dark box and elevated plus maze test) and remarkable increase in antidepressant activity (tail suspension test). The results suggest that methanol extract of Helianthus annuus exhibit significant antidepressant and moderate anxiolytic activity in tested animal models.en_US
dc.identifier.citationIslam Rubab Tarannum, Islam Ahmed Tanjimul, Hossain Mir Monir, Mazumder Kishor. Central nervous system activity of the methanol extracts of Helianthus annuus seeds in mice model. International Current Pharmaceutical Journal. 2015; 5(1): 1-4.en_US
dc.identifier.issn2224-9486
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/168014
dc.language.isoenen_US
dc.source.urihttps://www.banglajol.info/index.php/ICPJ/article/view/25869en_US
dc.subjectSunflower seedsen_US
dc.subjectasteraceaeen_US
dc.subjectgeneral behaviouren_US
dc.subjectantidepressant activityen_US
dc.subjectanxiolytic activityen_US
dc.titleCentral nervous system activity of the methanol extracts of Helianthus annuus seeds in mice model.en_US
dc.typeArticleen_US
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