Cytomorphological study of major salivary gland lesions with histopathological correlation.
No Thumbnail Available
Date
2024-12
Journal Title
Journal ISSN
Volume Title
Publisher
B.V.V. Sangha's S. Nijalingappa Medical College and HSK Hospital & Research Centre
Abstract
Background: Fine needle aspiration cytology (FNAC) is a very useful test for evaluating the salivary gland lesions. FNAC is useful to differentiate between benign and malignant and non-neoplastic lesions. A preoperative diagnosis will guide the surgeon to plan a surgery according to the nature of the tumor and proper management of the patient. FNAC is the most preferred method to biopsy because incisional biopsy is associated with the risk of contamination and infections. Methods: A prospective observational study was done in the pathology department of a medical college after obtaining approval from the institutional ethical committee. FNAC from all patients with salivary gland lesions and surgically resected specimens sent for histopathology. Results: A total of 173 cases were studied, of which 84 (48.55%) cases were reported as non-neoplastic lesions and 89 (51.44%) cases were reported as neoplastic lesions on FNAC. Among these, 71 (79.77%) cases were benign and 18 (20.22%) cases were malignant. Among non-neoplastic lesions, sialadenitis was the most common lesion. Pleomorphic adenoma and mucoepidermoid carcinoma were the most common benign and malignant lesions, respectively. Parotid gland was the most frequently involved gland. Histopathology correlation was seen in 66 cases that underwent surgery. Conclusion: FNAC is a safe, reliable, and accurate method of diagnosis of salivary gland lesions. FNAC provides effective information about salivary gland lesions and prevents unnecessary surgery of non-neoplastic lesions, and it can establish the diagnosis of the major salivary gland neoplastic lesions and can be recommended as an adjunct to histopathology.
Description
Keywords
Fine needle aspiration cytology, salivary gland neoplasm, pleomorphic adenoma
Citation
Marisetty Manikanta Swamy, Tamanara Sarojini Naidu, Thurlapati Satyaprakash . Cytomorphological study of major salivary gland lesions with histopathological correlation. . Medica Innovatica. 2024 Dec; 13(2): 64-71