A histological continuum between dentinogenesis imperfecta and dentin dysplasia: A case report with literature review
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Date
2019-07
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Society for Dental Research
Abstract
Dentinogenesis Imperfecta and dentin dysplasia are genetic oral diseases inherited in a simple autosomal dominant mode, with high penetrance and a low mutation rate. Both of them are present with bulbous crowns, marked cervical constrictions, severe attritions, few periapical radiolucencies, and premature tooth loss. The diagnosis is based on family history, and detailed clinical examination, while genetic diagnosis may become useful in the future once sufficient disease-causing mutations have been discovered. Here, we present a case with overlapping features of both dentinogenesis imperfecta and dentin dysplasia asserting both the anomalies to be part of the same continuum of the genetic event.
Description
Keywords
Dentin dysplasia, dentin sialophosphoprotein gene, dentinogenesis imperfecta
Citation
Gulati Nikita, Juneja Saurabh, Singh Akriti, Singh Iqbal. A histological continuum between dentinogenesis imperfecta and dentin dysplasia: A case report with literature review. Indian Journal of Dental Research. 2019 Jul; 30(4): 643-646