Comparison of Immunogenic Effect of Three Oil Adjuvant Vaccines against Haemorrhagic Septicaemia in Cattle and Buffalo

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dc.contributor.authorAfroz, Hinaen_US
dc.contributor.authorSattar, Sumiyyaen_US
dc.contributor.authorZamirm, Bushraen_US
dc.contributor.authorHaq, Ikram ulen_US
dc.contributor.authorRafique, Rehanen_US
dc.contributor.authorRasool, Asfaen_US
dc.date.accessioned2019-11-16T07:23:15Z
dc.date.available2019-11-16T07:23:15Z
dc.date.issued2016-04
dc.description.abstractHaemorrhagic Septicaemia is one of the most common, fatal and acute bacterial diseases of livestock which causes mortality above 70% and is caused by Pasteurella multocida. The only satisfactory and practical method of control and prevention is timely vaccination of all the healthy and in contact animals. Different types of vaccines are being used for the immunity against this disease. In this project three oil based vaccines were produced. Two single emulsion vaccines were prepared by utilizing Montanide ISA-50 and liquid paraffin with lanolin where as one double emulsion with the help of Montanide ISA-206 was prepared. In house quality control testing and safety testing was performed on swiss albino mice. For immune titre IHA was performed by collecting serum from each and every animal including control animals. The comparison of IHA was done via statistical analysis by using GMT, Single emulsion vaccine prepared from liquid paraffin with lanolin gave maximum immune titre out of all the three vaccines in large animals and in young calves ISA 206 gave a significant titre.en_US
dc.identifier.affiliationsVeterinary Research Institute, Zarrar Shaheed Road, Lahore, Pakistan.en_US
dc.identifier.affiliationsVeterinary Research Institute, Zarrar Shaheed Road, Lahore, Pakistan.en_US
dc.identifier.affiliationsVeterinary Research Institute, Zarrar Shaheed Road, Lahore, Pakistan.en_US
dc.identifier.affiliationsInstitute of Industrial Biotechnology, Government College University, Lahore, Pakistan.en_US
dc.identifier.affiliationsVeterinary Research Institute, Zarrar Shaheed Road, Lahore, Pakistan.en_US
dc.identifier.affiliationsVeterinary Research Institute, Zarrar Shaheed Road, Lahore, Pakistan.en_US
dc.identifier.citationAfroz Hina, Sattar Sumiyya, Zamirm Bushra, Haq Ikram ul, Rafique Rehan, Rasool Asfa. Comparison of Immunogenic Effect of Three Oil Adjuvant Vaccines against Haemorrhagic Septicaemia in Cattle and Buffalo. International Archives of BioMedical and Clinical Research. 2016 Apr-Jun; 2(2): 43-48en_US
dc.identifier.issn2454-9894
dc.identifier.issn2454-9886
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/184075
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber2en_US
dc.relation.volume2en_US
dc.source.urihttps://doi.org/10.21276/iabcr.2016.2.2.10en_US
dc.subjectHaemorrhagic Septicaemiaen_US
dc.subjectIHAen_US
dc.subjectcattleen_US
dc.subjectbuffaloen_US
dc.subjectmontanideen_US
dc.subjectISA 206en_US
dc.subjectISA-50en_US
dc.subjectliquid paraffinen_US
dc.subjectlanolinen_US
dc.subjectGMTen_US
dc.titleComparison of Immunogenic Effect of Three Oil Adjuvant Vaccines against Haemorrhagic Septicaemia in Cattle and Buffaloen_US
dc.typeJournal Articleen_US
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