Diagnostic value of serum adenosine deaminase in Type 2 diabetic patients

Simple item page
dc.contributor.authorKundu, Den_US
dc.contributor.authorSen, Sen_US
dc.contributor.authorPaul, Aen_US
dc.contributor.authorChatterjee, Aen_US
dc.contributor.authorSarkar, Pen_US
dc.contributor.authorChakrabarti, Ien_US
dc.date.accessioned2020-09-24T07:53:57Z
dc.date.available2020-09-24T07:53:57Z
dc.date.issued2019-02
dc.description.abstractBackground: Adenosine deaminase (ADA) is suggested to modulate the bioactivity of insulin, but its clinical significance in Type 2 diabetes mellitus (DM) is not yet established. The present study was undertaken to evaluate serum ADA activity and serum uric acid levels in patients of Type 2 DM. Aim: To evaluate the serum ADA level and to correlate ADA levels with Blood Glucose, Glycated Hemoglobin (HbA1c) levels in Type-2 DM patients. Material and Method: It is a case control study. The subjects in this study were divided into 3 groups. Group I consisted of 50 normal healthy individuals who served as controls with no history of DM. Group II consisted of 50 patients of Type 2 DM both males & females in the age group of 40-65 years on oral hypoglycemic drugs with HbA1c <7%. Group III consisted of 50 patients of Type 2 DM both males & females in the age group of 40-65 years on oral hypoglycemic drugs with HbA1c >7 %. Serum levels of fasting blood sugar, HbA1c, ADA and uric acid were estimated in all the subjects. Results: FBS, HbA1c, ADA and serum uric acid levels were found to be increased in the patients of Type 2 DM as compared with controls. Conclusion: It is concluded that there is an increase in serum ADA levels with increase in HbA1c levels. Serum uric acid levels increased with moderately increasing levels of HbA1c <7% and then decreased with further increasing levels of HbA1c >7% (a bell-shaped relation).en_US
dc.identifier.affiliationsAssociate Professor, Department of Biochemistry, Medical College Kolkata, West Bengal, Indiaen_US
dc.identifier.affiliationsAssociate Professor, Department of General Surgery, Medical College Kolkata, West Bengal, Indiaen_US
dc.identifier.affiliationsFinal Year PGT, Department of Biochemistry, Medical College Kolkata, West Bengal, Indiaen_US
dc.identifier.affiliationsFinal Year PGT, Department of Biochemistry, Medical College Kolkata, West Bengal, Indiaen_US
dc.identifier.affiliationsSecond Year PGT, Department of Biochemistry, Medical College Kolkata, West Bengal, Indiaen_US
dc.identifier.affiliationsSecond Year PGT, Department of Biochemistry, Medical College Kolkata, West Bengal, Indiaen_US
dc.identifier.citationKundu D, Sen S, Paul A, Chatterjee A, Sarkar P, Chakrabarti I. Diagnostic value of serum adenosine deaminase in Type 2 diabetic patients. International Journal of Medical Research & Review. 2019 Feb; 7(1): 1-7en_US
dc.identifier.issn2320-8686
dc.identifier.issn2321-127X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/205239
dc.languageenen_US
dc.publisherSiddharth Health Research and Social Welfare Societyen_US
dc.relation.issuenumber1en_US
dc.relation.volume7en_US
dc.source.urihttps://ijmrr.medresearch.in/index.php/ijmrr/article/view/1027en_US
dc.subjectType 2 Diabetes mellitusen_US
dc.subjectAdenosine deaminaseen_US
dc.subjectGlycated Hemoglobinen_US
dc.subjectUric aciden_US
dc.titleDiagnostic value of serum adenosine deaminase in Type 2 diabetic patientsen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijmrr2019v7n1p1.pdf
Size:
117.96 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Medical Research & Review