Diagnostic Assessment of Bone Marrow Aspiration Smears, Touch Imprints and Trephine Biopsy in Haematological Disorders.
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Date
2010-07
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Abstract
Diagnostic Assessment of bone marrow aspirate particle smears, imprints and biopsy sections was done
on 40 haematological disorders. Core needle biopsy of the bone marrow is a safe and useful procedure.
It is a valuable diagnostic aid for measurement of marrow cellularity and fibrosis.Bilateral trephine
biopsy was conducted wherever necessary.Bone marrow aspiration was the most effective method for
studying morphological details and was able to diagnose most of the cases except the 2 cases of
myelofibrosis which yielded dry tap for which trephine biopsy was diagnostic.Trephine biopsy was also
found to be superior for staging of lymphomas and to study the ALIP in MDS.Touch imprints were
useful for studying cell morphology, where aspiration yielded dry tap.All the three procedures of bone
marrow aspiration, trephine biopsy and touch imprints were found to be complementary to each other
and superiority of one method over the other depended on the specific disease process.
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Keywords
Hematological, Trephine Biopsy, Bone Marrow Aspiration
Citation
Gupta Nitin, Kumar Ram, Khajuria Arvind. Diagnostic Assessment of Bone Marrow Aspiration Smears, Touch Imprints and Trephine Biopsy in Haematological Disorders. JK Science Journal of Medical Education and Research. 2010 July-Sept; 12(3): 130-133