Prevalence of congenital anomalies at Srinagarind Hospital

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Date
2010-03-06
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Faculty of Medicine, Khon Kaen University
Abstract
Objective   :   To  evaluate  the  prevalence  of  congenital  anomalies   at  Srinagarind  Hospital.      Design   :   Descriptive  study   by   prospective  data  collection.Setting   : Srinagarind  Hospital,   Khon  Kaen  University.Subjective   :   All   mothers  and  their  anomalous  infants   who   were  born   at  Srinagarind  Hospital   between  1st  April   1997  and  31st  March   1998 . Intervention   :   Data  collection  of  the  anomalous  infants  and  their  mothers.  Main  outcome  measures   :   Prevalence  of congenital  anomalies .Results   :   This study revealed a 2.2 percent prevalence of congenital anomalies at Srinagarind Hospital during the study period (120 cases out of  5,420 total births). Among anomalous newborn cases, the male to female ratio was 1.7:1.  Seventy  eight  percent  of the anomalous infants were  considered  malformation .   Syndrome, sequence,  dysplasia,    deformation , association  and  disruption  were  found  to  be 11.7, 5.8, 1.7, 0.8, 0.8 and 0.8  percent  respectively.  Major  and  minor  congenital  anomalies were  found  to  be  64.2  and  35.8  percent respectively.  Common  major  congenital  anomalies  were  the abnormalities of gastrointestinal  system,     cardiovascular  system , chromosomal  abnormality ,  musculoskeletal  system  and  central  nervous  system  respectively.   Conclusion   :   Prevalence  of  congenital  anomalies  was  not  uncommon.  To  avoid    congenital  anomalies  or  provide proper  obstetrical  management ,  prenatal  diagnosis  should  be  offered  in  all  pregnant  women  especially  in  high-risk  groups.
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Citation
Srinagarind Medical Journal (SMJ); Vo. 19 No. 4 October-December 2004; 205-214