Association of dietary fiber with high sensitivity C-reactive proteinin type 2 diabetes mellitus.
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Date
2012-04
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Abstract
Introduction: Hs-CRP is a nonspecific marker of the inflammatory response has been associated with development
of type 2 diabetes mellitus. Cardiovascular disease is a major consequence of diabetes. DM confers
a 2-4 fold rise in cardiovascular risk compared with general population. One of the many modifiable risk factors
for both cardiovascular disease and diabetes is diet. Fiber is an important dietary factor that may modify
the risk of both diseases. Material & methods: The current study is an attempt to explore the association
of dietary fiber on inflammatory marker, hs-CRP in type2 diabetic subjects. Total 80 diabetic subjects were
included in this study of which 40 were taking more dietary fiber and 40 were taking relatively low dietary
fiber. Serum hs-CRP was measured by chemiluminescent immunometric assay (DPC Biermann Gmbh.,
Germany). Nutrient information was calculated using a pretested food recall questionnaire prepared by nutritionists
for usual Bangladeshi food articles. Results: Hs-CRP was significantly higher in subjects taking low
dietary fiber. There was significant negative correlation between CRP of subjects taking high and low intake
of dietary fiber. Conclusion: So, low dietary fiber consumption maybe a possible causal factor of raised CRP.
Type 2 diabetic patients who took less dietary fiber in their diets had elevated blood CRP levels.
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Keywords
Hs-CRP, High sensitivity C- reactive protein, Dietary fiber, T2DM, Type 2 Diabetes Mellitus
Citation
Begum I A, Sen M, Afrin S F, Moutoshi S S, Islam M A, Rahman M H. Association of dietary fiber with high sensitivity C-reactive proteinin type 2 diabetes mellitus. Bangladesh Journal of Medical Science. 2012; 11(2): 117-120.