Potentiation of hypoglycemic response of glibenclamide by piroxicam in rats and humans.

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dc.contributor.authorDiwan, P Ven_US
dc.contributor.authorSastry, M Sen_US
dc.contributor.authorSatyanarayana, N Ven_US
dc.date.accessioned2009-05-28T16:33:56Z
dc.date.available2009-05-28T16:33:56Z
dc.date.issued1992-04-01en_US
dc.description.abstractInfluence of piroxicam (PX) on glibenclamide (GL) induced hypoglycemia has been studied in rats, healthy human volunteers and diabetics. GL per se has significantly reduced blood sugar levels in rats and in humans. PX per se has significantly reduced BSLs, in diabetics, while having no significant influence on blood sugar level in rats and healthy human volunteers. Prior administration of PX has potentiated the hypoglycemic effect of GL in rats, healthy human volunteers and diabetics. GL, PX + GL administration have also significantly influenced the glucose tolerance test (GTT) in healthy human volunteers.en_US
dc.description.affiliationPharmacology Group, Indian Institute of Chemical Technology, Hyderabad.en_US
dc.identifier.citationDiwan PV, Sastry MS, Satyanarayana NV. Potentiation of hypoglycemic response of glibenclamide by piroxicam in rats and humans. Indian Journal of Experimental Biology. 1992 Apr; 30(4): 317-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/63392
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBlood Glucose --analysisen_US
dc.subject.meshDiabetes Mellitus, Type 2 --blooden_US
dc.subject.meshDrug Interactionsen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlyburide --therapeutic useen_US
dc.subject.meshHumansen_US
dc.subject.meshHypoglycemia --chemically induceden_US
dc.subject.meshMaleen_US
dc.subject.meshPiroxicam --pharmacologyen_US
dc.subject.meshRatsen_US
dc.titlePotentiation of hypoglycemic response of glibenclamide by piroxicam in rats and humans.en_US
dc.typeJournal Articleen_US
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