Antioxidant and nitric oxide synthase activation properties of Ganoderma applanatum.

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dc.contributor.authorAcharya, Krishnenduen_US
dc.contributor.authorYonzone, Parinitaen_US
dc.contributor.authorRai, Manjulaen_US
dc.contributor.authorRupa, Acharyaen_US
dc.date.accessioned2009-05-28T11:14:02Z
dc.date.available2009-05-28T11:14:02Z
dc.date.issued2005-10-21en_US
dc.description.abstractIn vitro evaluation of antioxidant activities of Ganoderma applanatum showed significant inhibition of lipid peroxidation, and potent hydroxyl radical scavenging activity when compared with standard drug catechin. IC50 values of crude, boiled and ethanolic extracts of G. applanatum were 604.8, 624 and 267 microg/ml, respectively in case of hydroxyl radical scavenging activity, and 441, 520.5 and 166.16 microg/ml, respectively in case of lipid peroxidation. Furthermore, crude, boiled and ethanolic extracts also increased significantly nitric oxide production (156.67, 121.88 and 742 pmole/mg dry wt/hr, respectively) over the control. The results of present investigation revealed that G. applanatum have potential therapeutic use.en_US
dc.description.affiliationDepartment of Botany, University of Calcutta, 35, Ballygange Circular Road, Kolkata 700 019, India. krishnendua@rediffmail.comen_US
dc.identifier.citationAcharya K, Yonzone P, Rai M, Rupa A. Antioxidant and nitric oxide synthase activation properties of Ganoderma applanatum. Indian Journal of Experimental Biology. 2005 Oct; 43(10): 926-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/56428
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAgaricalesen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntioxidants --pharmacologyen_US
dc.subject.meshCatechin --pharmacologyen_US
dc.subject.meshEnzyme Activationen_US
dc.subject.meshEthanol --metabolismen_US
dc.subject.meshGanoderma --metabolismen_US
dc.subject.meshHydroxyl Radicalen_US
dc.subject.meshInhibitory Concentration 50en_US
dc.subject.meshLipid Peroxidationen_US
dc.subject.meshNitric Oxide --metabolismen_US
dc.subject.meshNitric Oxide Synthase --metabolismen_US
dc.subject.meshPlant Extracts --pharmacologyen_US
dc.subject.meshReactive Oxygen Speciesen_US
dc.subject.meshSuperoxidesen_US
dc.titleAntioxidant and nitric oxide synthase activation properties of Ganoderma applanatum.en_US
dc.typeJournal Articleen_US
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