A multicentric study with arteether in patients of uncomplicated falciparum malaria.

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dc.contributor.authorAsthana, O Pen_US
dc.contributor.authorSrivastava, J Sen_US
dc.contributor.authorKamboj, V Pen_US
dc.contributor.authorValecha, Nen_US
dc.contributor.authorSharma, V Pen_US
dc.contributor.authorGupta, Sen_US
dc.contributor.authorPande, T Ken_US
dc.contributor.authorVishwanathan, K Aen_US
dc.contributor.authorMahapatra, K Men_US
dc.contributor.authorNayak, N Cen_US
dc.contributor.authorMahapatra, P Ken_US
dc.contributor.authorMahanta, Jen_US
dc.contributor.authorSrivastava, V Ken_US
dc.contributor.authorVasdev,en_US
dc.contributor.authorSingh, Nen_US
dc.contributor.authorShukla, M Men_US
dc.contributor.authorBalsara, A Ben_US
dc.contributor.authorMishra, S Ken_US
dc.contributor.authorSatpathy, S Ken_US
dc.contributor.authorMohanty, Sen_US
dc.contributor.authorDash, Ben_US
dc.date.accessioned2001-07-28en_US
dc.date.accessioned2009-05-31T01:06:16Z
dc.date.available2001-07-28en_US
dc.date.available2009-05-31T01:06:16Z
dc.date.issued2001-07-28en_US
dc.description.abstractTwo hundred and sixty seven patients of uncomplicated P. falciparum malaria completed study in a multicentric phase III clinical trial of Arteether. Arteether was given intramuscularly in a dose of 150 mg daily for three consecutive days. Each patient was followed upto 28 days of alpha, beta arteether therapy. The cure rate was 97% with fever clearance time between 1-7 days (24-168 hours) and parasite clearance time between 1-3 days (24-72 hours). Parasite reappearance rate was found to be 3% and reported at only three of the centres. Following the treatment no adverse effect was observed on haematological, biochemical and vital clinical parameters.en_US
dc.description.affiliationCentral Drug Research Institute, Lucknow, India.en_US
dc.identifier.citationAsthana OP, Srivastava JS, Kamboj VP, Valecha N, Sharma VP, Gupta S, Pande TK, Vishwanathan KA, Mahapatra KM, Nayak NC, Mahapatra PK, Mahanta J, Srivastava VK, Vasdev , Singh N, Shukla MM, Balsara AB, Mishra SK, Satpathy SK, Mohanty S, Dash B. A multicentric study with arteether in patients of uncomplicated falciparum malaria. Journal of the Association of Physicians of India. 2001 Jul; 49(): 692-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/91883
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAntimalarials --therapeutic useen_US
dc.subject.meshArtemisininsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMalaria, Falciparum --drug therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSesquiterpenes --therapeutic useen_US
dc.titleA multicentric study with arteether in patients of uncomplicated falciparum malaria.en_US
dc.typeClinical Trialen_US
dc.typeClinical Trial, Phase IIIen_US
dc.typeJournal Articleen_US
dc.typeMulticenter Studyen_US
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