Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient

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dc.contributor.authorKaur, Ramneeken_US
dc.contributor.authorMittal, Naveenen_US
dc.contributor.authorSoni, Ankitaen_US
dc.contributor.authorKaur, Harpreeten_US
dc.date.accessioned2025-05-09T09:57:04Z
dc.date.available2025-05-09T09:57:04Z
dc.date.issued2024-06
dc.description.abstractCryptococcosis usually occurs in immunocompromised patients and presents as meningitis and lung disease. Adrenal gland involvement may be observed, yet primary adrenal insufficiency by cryptococcal infection is infrequent. We present a case of a middle?aged immunocompetent man with primary adrenal insufficiency and bilateral adrenal lesions, splenomegaly, and miliary mottling in the lungs on imaging. No evidence of meningitis was witnessed. The clinico?radiological findings led toward the differential diagnosis of disseminated tuberculosis or fungal infection. Detection of cryptococcus organism was done on fine?needle aspiration cytology and biopsy on periodic acid?Schiff stain and Gomori`s methenamine silver stain. Thus, it is recommended to keep the possibility of cryptococcosis in mind while dealing with instances that have a tuberculosis?like clinico?radiological presentation. The detection of the causal organism on Fine needle aspiration (FNA)/biopsy examination may be useful in confirming the diagnosis and determining the appropriate medical treatment.en_US
dc.identifier.affiliationsDepartment of Pathology, Dayanand Medical College & Hospital, Ludhiana, Punjab, Indiaen_US
dc.identifier.affiliationsDepartment of Endocrinology, Dayanand Medical College & Hospital, Ludhiana, Punjab, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, Dayanand Medical College & Hospital, Ludhiana, Punjab, Indiaen_US
dc.identifier.affiliationsDepartment of Pathology, Dayanand Medical College & Hospital, Ludhiana, Punjab, Indiaen_US
dc.identifier.citationKaur Ramneek, Mittal Naveen, Soni Ankita, Kaur Harpreet. Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient. Indian Journal of Pathology & Microbiology. 2024 Jun; 67(2): 438-440en_US
dc.identifier.issn0377-4929
dc.identifier.issn0974-5130
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/245462
dc.languageenen_US
dc.publisherWolters Kluwer – Medknowen_US
dc.relation.issuenumber2en_US
dc.relation.volume67en_US
dc.source.urihttps://doi.org/10.4103/ijpm.ijpm_185_22en_US
dc.subjectAdrenalen_US
dc.subjectadrenal infectionen_US
dc.subjectcryptococcusen_US
dc.subjecttuberculosisen_US
dc.titleBilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patienten_US
dc.typeJournal Articleen_US
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