Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient
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Date
2024-06
Journal Title
Journal ISSN
Volume Title
Publisher
Wolters Kluwer – Medknow
Abstract
Cryptococcosis usually occurs in immunocompromised patients and presents as meningitis and lung disease. Adrenal gland involvement may be observed, yet primary adrenal insufficiency by cryptococcal infection is infrequent. We present a case of a middle?aged immunocompetent man with primary adrenal insufficiency and bilateral adrenal lesions, splenomegaly, and miliary mottling in the lungs on imaging. No evidence of meningitis was witnessed. The clinico?radiological findings led toward the differential diagnosis of disseminated tuberculosis or fungal infection. Detection of cryptococcus organism was done on fine?needle aspiration cytology and biopsy on periodic acid?Schiff stain and Gomori`s methenamine silver stain. Thus, it is recommended to keep the possibility of cryptococcosis in mind while dealing with instances that have a tuberculosis?like clinico?radiological presentation. The detection of the causal organism on Fine needle aspiration (FNA)/biopsy examination may be useful in confirming the diagnosis and determining the appropriate medical treatment.
Description
Keywords
Adrenal, adrenal infection, cryptococcus, tuberculosis
Citation
Kaur Ramneek, Mittal Naveen, Soni Ankita, Kaur Harpreet. Bilateral adrenal cryptococcosis causing adrenal insufficiency in an immunocompetent patient. Indian Journal of Pathology & Microbiology. 2024 Jun; 67(2): 438-440