Association of Glycosylated Haemoglobin Level with the Severity of Coronary Artery Disease in NSTEMI Diabetic Patients.

dc.contributor.authorSalim, Mahmod Mohammad
dc.contributor.authorFazila-Tun-Nesa, Malik
dc.contributor.authorArif Rahman, Mohammad
dc.contributor.authorHossain, Mohammad Delwar
dc.contributor.authorMasum, Mandal Md Raihan
dc.date.accessioned2015-12-17T04:07:38Z
dc.date.available2015-12-17T04:07:38Z
dc.date.issued2015
dc.description.abstractBackground: Relation between diabetes mellitus and ischemic heart disease is well established. But the effect of HbA1C on severity of coronary artery disease remains uncertain in non-ST elevation myocardial infarction and diabetic patient. Objective of our study was to know the relationship of HbA1C with the severity of coronary artery disease. Methods: In this cross sectional analytical study a total of 104 NSTEMI diabetic patients were enrolled by purposive sampling. They were divided into two groups according to the level of HbA1C, Group-I patients having HbA1C<7% and Group-II patients having HbA1C >7%. Vessel score and Gensini score was calculated from coronary angiogram and compared between groups. Results: Single vessel disease were significantly higher in group-I compared to Group-II( 38.5% vs 7.7% in Group-I vs Group-II,p<0.05). Double vessel disease were higher in group-II compared to Group-I but the difference was statistically not significant (42.3% vs 48.1% in Group-I vs Group-II respectively (p>0.05). Triple vessel disease were significantly higher in group-II compared to Group- I (19.2% vs 44.4% in Group-I vs Group-II,p<0.05). Mean Vessel score was higher in Group-II compared to Group-I(1.73 ± 0.86 vs 2.50 ±0.70 in Group-I vs Group-II, p<0.05). Mean Gensini score was higher in Group-II compared to Group-I (44.6 ± 38.4 vs 76.9 ± 44.6 in Group-I vs Group-II, p<0.05). There were significant positive linear correlation between HbA1C and Vessels score and Gensini score (p<0.05). Conclusion: This study may be concluded that the presence of HbA1C >7% are associated with of severe coronary artery disease in NSTEMI with diabetes mellitusen_US
dc.identifier.citationSalim Mahmod Mohammad, Fazila-Tun-Nesa Malik, Arif Rahman Mohammad, Hossain Mohammad Delwar, Masum Mandal Md Raihan. Association of Glycosylated Haemoglobin Level with the Severity of Coronary Artery Disease in NSTEMI Diabetic Patients. Cardiovascular Journal. 2015; 8(1): 43-48.en_US
dc.identifier.issn2071-0917
dc.identifier.issn2309-6357
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/168347
dc.language.isoenen_US
dc.source.urihttps://www.banglajol.info/index.php/CARDIO/article/view/24767en_US
dc.subjectHbA1Cen_US
dc.subjectCoronary Artery Diseaseen_US
dc.titleAssociation of Glycosylated Haemoglobin Level with the Severity of Coronary Artery Disease in NSTEMI Diabetic Patients.en_US
dc.typeArticleen_US
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