Association of Glycosylated Haemoglobin Level with the Severity of Coronary Artery Disease in NSTEMI Diabetic Patients.
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Date
2015
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Abstract
Background: Relation between diabetes mellitus and ischemic heart disease is well established.
But the effect of HbA1C on severity of coronary artery disease remains uncertain in non-ST
elevation myocardial infarction and diabetic patient. Objective of our study was to know the
relationship of HbA1C with the severity of coronary artery disease.
Methods: In this cross sectional analytical study a total of 104 NSTEMI diabetic patients were
enrolled by purposive sampling. They were divided into two groups according to the level of HbA1C,
Group-I patients having HbA1C<7% and Group-II patients having HbA1C >7%. Vessel score and
Gensini score was calculated from coronary angiogram and compared between groups.
Results: Single vessel disease were significantly higher in group-I compared to Group-II( 38.5% vs
7.7% in Group-I vs Group-II,p<0.05). Double vessel disease were higher in group-II compared to
Group-I but the difference was statistically not significant (42.3% vs 48.1% in Group-I vs Group-II
respectively (p>0.05). Triple vessel disease were significantly higher in group-II compared to Group-
I (19.2% vs 44.4% in Group-I vs Group-II,p<0.05). Mean Vessel score was higher in Group-II compared
to Group-I(1.73 ± 0.86 vs 2.50 ±0.70 in Group-I vs Group-II, p<0.05). Mean Gensini score was higher
in Group-II compared to Group-I (44.6 ± 38.4 vs 76.9 ± 44.6 in Group-I vs Group-II, p<0.05). There
were significant positive linear correlation between HbA1C and Vessels score and Gensini score
(p<0.05).
Conclusion: This study may be concluded that the presence of HbA1C >7% are associated with of
severe coronary artery disease in NSTEMI with diabetes mellitus
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Keywords
HbA1C, Coronary Artery Disease
Citation
Salim Mahmod Mohammad, Fazila-Tun-Nesa Malik, Arif Rahman Mohammad, Hossain Mohammad Delwar, Masum Mandal Md Raihan. Association of Glycosylated Haemoglobin Level with the Severity of Coronary Artery Disease in NSTEMI Diabetic Patients. Cardiovascular Journal. 2015; 8(1): 43-48.