A prospective study of risk factor profile & incidence of deep venous thrombosis among medically-ill hospitalized patients at a tertiary care hospital in northern India.

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dc.contributor.authorSharma, Surendra K
dc.contributor.authorGupta, Varun
dc.contributor.authorKadhiravan, Tamilarasu
dc.contributor.authorBanga, Amit
dc.contributor.authorSeith, Ashu
dc.contributor.authorKumar, Atin
dc.contributor.authorSaxena, Renu
dc.contributor.authorThabah, Molly M
dc.contributor.authorGulati, Vandana
dc.contributor.authorBhatia, Indrish
dc.contributor.authorKavimandan, Amit A
dc.date.accessioned2011-12-19T04:41:22Z
dc.date.available2011-12-19T04:41:22Z
dc.date.issued2009-12
dc.description.abstractBackground & objectives: Hospitalization for medical-illness is associated with an increased risk of deep venous thrombosis (DVT). However, there are no published data from India addressing at this issue. We sought to study the risk factor profile and the incidence of DVT among hospitalized medically-ill patients, a tertiary care hospital in northern India. Methods: All adults admitted to the medical wards and intensive care unit with level 1 or 2 mobility over a period of two years (July 2006 to July 2008) at the All India Institute of Medical Sciences hospital, New Delhi, were prospectively studied. Patients having DVT at admission or an anticipated hospital stay less than 48 h were excluded. The presence of clinical risk factors for DVT was recorded and laboratory evaluation was done for hypercoagulable state. A routine surveillance venous compression Doppler ultrasonography was performed 12 ± 8 days after hospital admission. Results: Of the 163 patients, 77 (47%) had more than one risk factor for DVT. Five (3%) patients developed DVT; none of them had symptomatic DVT. None of these patients received anticoagulation prior to the development of DVT. The mean age of those who developed DVT was 40 ± 13 (25-50) yr; two of five were male. The incidence rate of DVT was 2.7 per 1000 person-days of hospital stay [95% confidence interval (CI): 0.87 to 6.27]. None of the factors was found to be significantly associated with the risk of DVT. Interpretation & conclusions: In our setting, although many hospitalized medically-ill patients had risk factors for DVT, the absolute risk of DVT was low compared to the western population but clearly elevated compared to non hospitalized patients. Large studies from India are required to confirm our findings.en_US
dc.identifier.citationSharma Surendra K, Gupta Varun, Kadhiravan Tamilarasu, Banga Amit, Seith Ashu, Kumar Atin, Saxena Renu, Thabah Molly M, Gulati Vandana, Bhatia Indrish, Kavimandan Amit A. A prospective study of risk factor profile & incidence of deep venous thrombosis among medically-ill hospitalized patients at a tertiary care hospital in northern India. Indian Journal of Medical Research. 2009 Dec; 130(6): 726-730.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/135949
dc.language.isoenen_US
dc.source.urihttps://icmr.nic.in/ijmr/2009/december/1209.pdfen_US
dc.subjectDeep venous thrombosisen_US
dc.subjectintensive care uniten_US
dc.subjectmedical illnessen_US
dc.subjectpulmonary embolismen_US
dc.subjectvenous compression ultrasonographyen_US
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAged, 80 and over
dc.subject.meshFemale
dc.subject.meshHospitalization
dc.subject.meshHumans
dc.subject.meshIndia --epidemiology
dc.subject.meshIntensive Care Units
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshProspective Studies
dc.subject.meshRisk Factors
dc.subject.meshVenous Thrombosis --epidemiology
dc.subject.meshVenous Thrombosis --etiology
dc.subject.meshYoung Adult
dc.titleA prospective study of risk factor profile & incidence of deep venous thrombosis among medically-ill hospitalized patients at a tertiary care hospital in northern India.en_US
dc.typeArticleen_US
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