A prospective study of risk factor profile & incidence of deep venous thrombosis among medically-ill hospitalized patients at a tertiary care hospital in northern India.
Loading...
Date
2009-12
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Background & objectives: Hospitalization for medical-illness is associated with an increased risk of deep
venous thrombosis (DVT). However, there are no published data from India addressing at this issue.
We sought to study the risk factor profile and the incidence of DVT among hospitalized medically-ill
patients, a tertiary care hospital in northern India.
Methods: All adults admitted to the medical wards and intensive care unit with level 1 or 2 mobility over
a period of two years (July 2006 to July 2008) at the All India Institute of Medical Sciences hospital, New
Delhi, were prospectively studied. Patients having DVT at admission or an anticipated hospital stay less
than 48 h were excluded. The presence of clinical risk factors for DVT was recorded and laboratory
evaluation was done for hypercoagulable state. A routine surveillance venous compression Doppler
ultrasonography was performed 12 ± 8 days after hospital admission.
Results: Of the 163 patients, 77 (47%) had more than one risk factor for DVT. Five (3%) patients developed
DVT; none of them had symptomatic DVT. None of these patients received anticoagulation prior to the
development of DVT. The mean age of those who developed DVT was 40 ± 13 (25-50) yr; two of five were
male. The incidence rate of DVT was 2.7 per 1000 person-days of hospital stay [95% confidence interval
(CI): 0.87 to 6.27]. None of the factors was found to be significantly associated with the risk of DVT.
Interpretation & conclusions: In our setting, although many hospitalized medically-ill patients had risk
factors for DVT, the absolute risk of DVT was low compared to the western population but clearly elevated compared to non hospitalized patients. Large studies from India are required to confirm our findings.
Description
Keywords
Deep venous thrombosis, intensive care unit, medical illness, pulmonary embolism, venous compression ultrasonography
Citation
Sharma Surendra K, Gupta Varun, Kadhiravan Tamilarasu, Banga Amit, Seith Ashu, Kumar Atin, Saxena Renu, Thabah Molly M, Gulati Vandana, Bhatia Indrish, Kavimandan Amit A. A prospective study of risk factor profile & incidence of deep venous thrombosis among medically-ill hospitalized patients at a tertiary care hospital in northern India. Indian Journal of Medical Research. 2009 Dec; 130(6): 726-730.