Toxic effects of different concentrations of dimethoate on lysosomal enzymes of female albino rats.

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dc.contributor.authorReddy, P Nen_US
dc.contributor.authorRaj, G Den_US
dc.contributor.authorDhar, S Cen_US
dc.date.accessioned2009-05-28T11:13:13Z
dc.date.available2009-05-28T11:13:13Z
dc.date.issued1992-05-01en_US
dc.description.abstractThe effect of three different concentrations of dimethoate on the activity of certain lysosomal enzymes, viz. beta-glucuronidase, beta-N-acetylglucosaminidase, cathepsin B and cathepsin D in serum, skin, liver, kidney and spleen and the stability of liver and kidney lysosomes was studied in female albino rats. The activity of beta-glucuronidase, beta-N-acetylglucosaminidase, cathepsin D was found to increase in serum and tissues in higher concentration (2.25 mg/100 g body weight) of dimethoate treated rats. A significant increase in the rate of release of beta-glucuronidase was found in the liver and kidney of higher concentration of dimethoate treated rats compared to controls. The results demonstrate that the activity of lysosomal enzymes increased in higher concentration of dimethoate treated rats than the lower concentration (0.56 mg/100 g body weight) of dimethoate treated rats.en_US
dc.description.affiliationBiochemistry Laboratory, Central Leather Research Institute, Madras, India.en_US
dc.identifier.citationReddy PN, Raj GD, Dhar SC. Toxic effects of different concentrations of dimethoate on lysosomal enzymes of female albino rats. Indian Journal of Experimental Biology. 1992 May; 30(5): 394-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/56408
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDimethoate --administration & dosageen_US
dc.subject.meshDose-Response Relationship, Drugen_US
dc.subject.meshFemaleen_US
dc.subject.meshLysosomes --drug effectsen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistar --metabolismen_US
dc.subject.meshSkin --enzymologyen_US
dc.subject.meshViscera --enzymologyen_US
dc.titleToxic effects of different concentrations of dimethoate on lysosomal enzymes of female albino rats.en_US
dc.typeJournal Articleen_US
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