Updated therapeutic approach in the management of Polycystic Ovary Syndrome (PCOS): A Review
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Date
2019-04
Journal Title
Journal ISSN
Volume Title
Publisher
Society for research and Development in Education
Abstract
Polycystic ovary syndrome (PCOS) is a heterogeneous clinical entity that is defined as the association of hyperandrogenism with chronic an ovulation in women without specific underlying diseases of the adrenal or pituitary glands. PCOS is also associated with a metabolic disturbance with complex inter relation of obesity, insulin resistance and endocrine abnormalities remains unresolved. However, several studies link obesity, body fat distribution and nutritional habits with the hormonal and metabolic profiles of PCOS. Moreover, intervention studies have suggested that reducing weight and hyper insulinaemia either by diet alone or by a combination of diet with drugs improves hirsutism, fertility, hormonal and metabolic profiles of PCOS. In fact, the evaluation of nutritional factors in PCOS is helpful for the screening of metabolic abnormalities and the management of women with PCOS. A point of particular interest in the management of PCOS is that the choice of contraception remains difficult in these high cardiovascular risk women. The lack of prospective studies to evaluate long-term metabolic and cardiovascular tolerance necessitates care and the assessment of other hormonal possibilities
Description
Keywords
Polycystic ovary syndrome, metabolic disorder, Contraceptives
Citation
Kaul Aayushi, Zar Nidhi, Shangloo Shruti, Nain Parminder. Updated therapeutic approach in the management of Polycystic Ovary Syndrome (PCOS): A Review. International Journal of Research and Development in Pharmacy & Life Sciences (IJRDPL). 2019 Apr; 8(2): 37-42