A serious warning: A case report on localized amyloidosis of the oral cavity

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dc.contributor.authorJohn, Sen_US
dc.contributor.authorSubba, Pen_US
dc.contributor.authorAramugam, Aen_US
dc.contributor.authorGupta, Sen_US
dc.contributor.authorKhanna, Ren_US
dc.date.accessioned2025-06-19T05:55:12Z
dc.date.available2025-06-19T05:55:12Z
dc.date.issued2025-03
dc.description.abstractAmyloidosis is a relatively rare condition with an array of complex pathophysiology. Localized amyloidosis is a rare and benign condition that practically never results in any clinical repercussions in the head and neck area. Multiple soft nodules of the tongue, lip, and cheek are the most commonly described defining characteristics of localized oral amyloidosis. These nodules originate due to the proliferation of abnormally folded protein aggregates in the body’s extracellular tissue compartments, which destroy organ structure and function. Herein, we address the case of a female infant aged one with a smooth nodule in the labial mucosa who was diagnosed with primary localized amyloidosis. When a patient is diagnosed with amyloidosis of the oral mucosa, the possibility of systemic amyloidosis or an underlying plasma cell dyscrasia must be ruled out. Surgical treatment may be beneficial for eliminating any functional impairment if primary localized amyloidosis is established.en_US
dc.identifier.affiliationsDepartment of Oral and Maxillofacial Pathology, King George’s Medical University, Lucknow, Uttar Pradesh, India, 1 Department of Preventive and Pediatric Dentistry, King George’s Medical University, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Preventive and Pediatric Dentistry, King George’s Medical University, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Oral and Maxillofacial Pathology, King George’s Medical University, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Preventive and Pediatric Dentistry, King George’s Medical University, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.citationJohn S, Subba P, Aramugam A, Gupta S, Khanna R. A serious warning: A case report on localized amyloidosis of the oral cavity. Indian Journal of Pathology & Microbiology. 2025 Mar; 68(1): 212-215en_US
dc.identifier.issn0377-4929
dc.identifier.issn0974-5130
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/249956
dc.languageenen_US
dc.publisherWolters Kluwer - Medknowen_US
dc.relation.issuenumber1en_US
dc.relation.volume68en_US
dc.source.urihttps://doi.org/10.4103/ijpm.ijpm_720_23en_US
dc.subjectAmyloidosisen_US
dc.subjectkappa chainsen_US
dc.subjectlambda chainsen_US
dc.subjectserum amyloid p componenten_US
dc.titleA serious warning: A case report on localized amyloidosis of the oral cavityen_US
dc.typeJournal Articleen_US
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