COMPARATIVE ANALYSIS OF HAEMATOLOGICAL PARAMETERS AMONG INFREQUENT AND REGULAR REPEAT WHOLE BLOOD DONORS IN A TERTIARY CARE CENTRE-A PILOT STUDY

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dc.contributor.authorP, Dr. Parvathy Mohanen_US
dc.contributor.authorA P, Dr. Poornimaen_US
dc.contributor.authorS, Dr. Maya Devien_US
dc.date.accessioned2023-08-09T05:59:55Z
dc.date.available2023-08-09T05:59:55Z
dc.date.issued2023-07
dc.description.abstractBlood transfusion service is a vital part of our health care system. Stringent blood donor screening and medical examination plays a vital role in maintaining the quality and safety of blood components. Voluntary non-remunerated blood donors form the backbone of blood transfusion services. However, regular donation by such voluntary donors may cause significant depletion of iron stores in the body. This has the potential to adversely affect the donor's health, and also to lower the quality of blood being collected subsequently. Even though a pre-donation hemoglobin estimation is routinely done in blood centres, it may fail to recognize subclinical iron store depletion. Testing Ferritin level of all donors is not cost effective and practical in resource limited centres. This study was aimed to identify any significant changes in hematological parameters over repeated blood donations, that may point towards a potential Iron deficiency in an otherwise healthy donor. This was a cross sectional study involving 138 whole blood donors who had attended the blood centre, Department of Transfusion Medicine, Government Medical college, Thiruvananthapuram. The study subjects were categorized into 2 groups based on the number of donations and a Complete blood count (CBC) was done for each group. Data was analyzed using SPSS software, quantitative variables expressed as Mean and Standard Deviation, p value <0.05 was considered statistically significant. Results were analysed by Independent Samples T test. Statistically significant variables were further analysed using Kruskal-Wallis test. Second time blood donors constituted major part of sample size (20/138). Mean Hemoglobin value showed no significant change among the two donor categories. Mean corpuscular volume (MCV) of repeat whole blood donors is significantly lower than infrequent donors independent samples T test, tvalue=3.309. (p-value=0.001). Donors were further subdivided into 5 groups in the order of increasing number of donations and significant difference was observed in MCV and proved by Kruskal-Wallis test(H=19.1344) As per our study, a significant reduction in MCV among repeat donors with a normal hemoglobin value compared to infrequent donors. This might point towards an impending Iron deficiency anemia in near future. A prompt detection of subclinical iron deficiency in voluntary blood donors is the need of the hour since it can cause adverse consequences in donor health and can considerably lower the donor availability as well. Blood centres should take measures like routine Iron stores evaluation of regular repeat donors, educating donors regarding the importance of maintaing a healthy diet, Iron tablet supplementation to prevent donor Iron deficiency anemia (IDA) etc.en_US
dc.identifier.affiliationsJunior Resident, Department of Transfusion Medicine, Government Medical College, Thiruvananthapuram, Kerala, Indiaen_US
dc.identifier.affiliationsAssistant Professor, Department of Transfusion Medicine, Government Medical College, Thiruvananthapuram, Kerala, Indiaen_US
dc.identifier.affiliationsProfessor and HOD, Department of Transfusion Medicine, Government Medical College, Thiruvananthapuram, Kerala, India.en_US
dc.identifier.citationP Dr. Parvathy Mohan, A P Dr. Poornima, S Dr. Maya Devi. COMPARATIVE ANALYSIS OF HAEMATOLOGICAL PARAMETERS AMONG INFREQUENT AND REGULAR REPEAT WHOLE BLOOD DONORS IN A TERTIARY CARE CENTRE-A PILOT STUDY. Indian Journal Of Applied Research. 2023 Jul; 13(7): 1-2en_US
dc.identifier.issn2249-555X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/221451
dc.languageenen_US
dc.publisherIndian Society For Health And Advanced Researchen_US
dc.relation.issuenumber7en_US
dc.relation.volume13en_US
dc.source.urihttps://www.doi.org/10.36106/ijaren_US
dc.subjectRegular voluntary donorsen_US
dc.subjectMean Corpuscular volume (MCV)en_US
dc.subjectHaemoglobinen_US
dc.titleCOMPARATIVE ANALYSIS OF HAEMATOLOGICAL PARAMETERS AMONG INFREQUENT AND REGULAR REPEAT WHOLE BLOOD DONORS IN A TERTIARY CARE CENTRE-A PILOT STUDYen_US
dc.typeJournal Articleen_US
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