Prolonged stability of R plasmids KR61 and KR61-A in Salmonella host.

Simple item page
dc.contributor.authorKhatoon, Hen_US
dc.contributor.authorJahan, Nen_US
dc.date.accessioned2009-05-28T13:00:02Z
dc.date.available2009-05-28T13:00:02Z
dc.date.issued1995-04-01en_US
dc.description.abstractThe R plasmids, KR61 and KR61-A, that were originally isolated from a clinical strain of Aerobacter aerogenes in 1971 and determined resistance to kanamycin (Km), neomycin (Nm), streptomycin (Sm), tetracycline (Tc); and ampicillin (Ap) respectively were found stable in Salmonella typhimurium LT2 even after 22 years of cultivation on antibiotic free media. KR61, carrying resistance to KmNmSmTc, not only maintained all its resistances but also maintained its conjugal transferability (RTF) as indicated by its subsequent transfer to Escherichia and Salmonella hosts. KR61-A that carried resistance to Ap and lacked an RTF could be mobilized by KR61 from S. typhimurium LT2, constructed to bear KR61-A and KR61, to E. coli recipients. S. typhimurium LT2 carrying KR61-A + KR61 (ApKmNmSmTc), showed the characteristic conjugal transfer of resistances in following three patterns: (i) Ap, (ii) KmNmSmTc and (iii) ApKmNmSmTc. The findings reported here are based on conjugal isolation of plasmids. Physical isolation of KR61 and KR61-A was never made.en_US
dc.description.affiliationDepartment of Microbiology, University of Karachi, Pakistan.en_US
dc.identifier.citationKhatoon H, Jahan N. Prolonged stability of R plasmids KR61 and KR61-A in Salmonella host. Indian Journal of Experimental Biology. 1995 Apr; 33(4): 309-10en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/58830
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshR Factorsen_US
dc.subject.meshSalmonella typhimurium --geneticsen_US
dc.subject.meshTime Factorsen_US
dc.titleProlonged stability of R plasmids KR61 and KR61-A in Salmonella host.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Experimental Biology