Lipedema: A Clinical Challenge-revisited.
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Date
2015
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Abstract
Lipedema is a disfiguring disorder with abnormal and progressive deposition of adipose tissue in
the hips and lower extremities almost exclusively occurring in women. There is a hereditary
tendency and a substantial variability in disease severity. Lipedema is often misdiagnosed as
lymphedema or morbid obesity. The etiology and pathogenesis are not understood. Early
diagnosis and treatment are critical to minimize physical and psychological morbidity. The
diagnosis is usually made by history and clinical examination. Non-invasive imaging techniques
such as computed tomography or magnetic resonance can differentiate lipedema from other
causes of edematous lower extremities. Lymphoscintigraphy may be helpful in cases which are
associated with lymphedema (lipo-lymphedema). Management with manual lymphatic drainage
and compression therapy are considered the most appropriate treatment. Use of conventional
liposuction is controversial since it may further damage the lymphatic vessels. Newer techniques
such as tumescent micro annular laser assisted liposuction and water jet-assisted liposuction have
shown some promising results. Variety of other surgical procedures combined with manual
lymphatic drainage and tailored post-surgical care are under investigation.
Description
Keywords
Lipedema, lipo-lymphedema, obesity, manual lymphatic drainage, liposuction
Citation
Omaira Mohammad, Mehrotra Avanti, Fankhauser Margaret J, Hrinczenko Borys, Dimitrov Nikolay V. Lipedema: A Clinical Challenge-revisited. British Journal of Medicine and Medical Research. 2015; 5(11): 1328-1337.