Residue Analysis of Oxytetracycline in Milk Sample by Two Different Chromatographic Methods and Determination of Ionization Constant Values

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dc.contributor.authorSardoğan, Seyfien_US
dc.contributor.authorŞanlı, Senemen_US
dc.contributor.authorSardoğan, Barışen_US
dc.contributor.authorAtalay, Barışen_US
dc.date.accessioned2020-11-18T10:30:18Z
dc.date.available2020-11-18T10:30:18Z
dc.date.issued2020-08
dc.description.abstractIn thepresent study, two analytical methods for the residue analysis of oxytetracycline in milk sample have been generated. InHPLC method, the analysis was performed on an X Terra RP-18 column at 25 °C with the mobile phase as methanol: water (20 : 80 )(v/v) modified to pH 5. For the second method capillary electrophoresis system was used. The analysis of oxytetracycline in milk sample could be achieved without using organic modifier in a 58 cm length capillary at a working voltage of 12 kV with 20 mM NaH2PO4-H3PO4(pH 7) by capillary electrophoresis. Tetracycline was used as internal standard in both methods. The results calculatedfrom both methods were compared to each other. The calculated data for drugs was checked with the data predicted by the SPARC on-line pKa estimatoren_US
dc.identifier.affiliationsDepartment of Food Engineering, Faculty of Engineering, Uşak University, Uşak, Turkeyen_US
dc.identifier.affiliationsDepartment of Chemistry, Faculty of Science and Arts, Uşak University, Uşak, Turkeyen_US
dc.identifier.affiliationsDepartment of Medical Laboratory Techniques, Vocational School of Health Services, Uşak University, Uşak, Turkeyen_US
dc.identifier.affiliationsDepartment of Rectorate, Uşak University, Uşak, Turkeyen_US
dc.identifier.affiliationsİzmir Kavram Vocational College of Higher Education, İzmir, Turkeyen_US
dc.identifier.citationSardoğan Seyfi, Şanlı Senem, Sardoğan Barış, Atalay Barış. Residue Analysis of Oxytetracycline in Milk Sample by Two Different Chromatographic Methods and Determination of Ionization Constant Values. Journal of Pharmaceutical Research International. 2020 Aug; 32(15): 1-9en_US
dc.identifier.issn2456-9119
dc.identifier.issn2231-2919
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/215868
dc.languageenen_US
dc.publisherSCIENCEDOMAIN internationalen_US
dc.relation.issuenumber15en_US
dc.relation.volume32en_US
dc.source.urihttps://doi.org/10.9734/JPRI/2020/v32i1530618en_US
dc.subjectOxytetracyclineen_US
dc.subjectmilken_US
dc.subjectresidue analysisen_US
dc.subjectHPLCen_US
dc.subjectcapillary electrophoresisen_US
dc.titleResidue Analysis of Oxytetracycline in Milk Sample by Two Different Chromatographic Methods and Determination of Ionization Constant Valuesen_US
dc.typeJournal Articleen_US
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