The Role of Twist1 in Stem Cell Differentiation through Mechanical Cues: A Review and Hypothesis.
dc.contributor.author | Yan, Yinqiu | |
dc.contributor.author | Tian, Zeyun | |
dc.contributor.author | Guan, Qiuyue | |
dc.contributor.author | Bai, Ding | |
dc.contributor.author | Zhang, Jing | |
dc.contributor.author | Han, Xianglong | |
dc.date.accessioned | 2017-02-10T12:16:54Z | |
dc.date.available | 2017-02-10T12:16:54Z | |
dc.date.issued | 2016 | |
dc.description.abstract | Due to the pivotal role of stem cell differentiation in regeneration and disease cure, the study of it has always been a research highlight during the recent years. Stress microenvironment has a great impact on cell growth, proliferation, differentiation and apoptosis. Twist1, as a core epithelial-mesenchymal transition (EMT) regulatory factor, plays an important role in these processes. Moreover, Twist1 gene can express in alveolar bone – periodontal ligament interface and the expression can be regulated by changes in the occlusal force. In this article, we will present a review of Twist1 gene, especially in the aspect of the biological functions in stem cell differentiation under mechanical signals and explore whether Twist1 involved in tissue remodeling in alveolar bone - periodontal membrane interface under stress. | en_US |
dc.identifier.citation | Yan Yinqiu, Tian Zeyun, Guan Qiuyue, Bai Ding, Zhang Jing, Han Xianglong. The Role of Twist1 in Stem Cell Differentiation through Mechanical Cues: A Review and Hypothesis. British Journal of Medicine and Medical Research. 2016; 17(1):1-9. | en_US |
dc.identifier.issn | 2231-0614 | |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/183454 | |
dc.language.iso | en | en_US |
dc.source.uri | https://www.sciencedomain.org/abstract/15528 | en_US |
dc.subject | Twist1 | en_US |
dc.subject | stem cell differentiation | en_US |
dc.subject | stress microenvironment | en_US |
dc.subject | alveolar bone – periodontal ligament interface | en_US |
dc.title | The Role of Twist1 in Stem Cell Differentiation through Mechanical Cues: A Review and Hypothesis. | en_US |
dc.type | Article | en_US |
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