A Study on Socio-Demographic and Clinical Profile of Patients on Second Line Anti-Retroviral Therapy Registered at ART Centre in Surat City

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dc.contributor.authorParmar, Gen_US
dc.contributor.authorParmar, Sen_US
dc.contributor.authorAmin, SSen_US
dc.contributor.authorPatel, NBen_US
dc.date.accessioned2025-08-13T09:54:23Z
dc.date.available2025-08-13T09:54:23Z
dc.date.issued2025-06
dc.description.abstractBackground: There is a need to develop concrete data in India about the number of people who need to switch to second-line HIV drugs and widespread emergence of drug resistance threatens the sustainability of the national programme. This study was conducted to study on Socio-Demographic and Clinical Profile of Patients on Second Line Anti-Retroviral Therapy Registered at ART Centre in Surat City. Methodology: The present study was a Cross-sectional study conducted at the ART centre of Gujarat, which are providing free second line ART. The study was conducted by pretested semi-structured questionnaire. The information regarding socio-demography and clinical variables, treatment and sexual activity were taken by oral interview of patients. While information regarding laboratory profile, adherence and treatment history were taken from patient treatment cards. Results: Most common reason for switch to second line ART was virological failure (84.2%). Mean duration of first line ART treatment was 30.15 (S.D. 25.350) months. All patients were given ritonavir boosted PI. Majority (66.7%) were given Atazinavir-ritonavir boosted PI and around 30% had history of substitution within second line ART. Conclusion: On the basis of our findings, we conclude that early detection of first-line treatment failure and improve availability/affordability of second-line regimens should become priorities in National Programme. First line ART patients with history of tuberculosis following ART initiation, treatment interruptions, treatment from private facility, belonging to nuclear family and lower social-economic class should be watched for ART failure.en_US
dc.identifier.affiliationsDepartment of Community Medicine, RKDF Medical College Hospital and Research Centre, Bhopal, Madhya Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Community Medicine, RKDF Medical College Hospital and Research Centre, Bhopal, Madhya Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Respiratory Medicine, ACPM Medical College, Dhule, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Community Medicine, School of Medical Sciences Medical College, Sri Satya Sai University of Technology and Medical Sciences Sehore, Madhya Pradeshen_US
dc.identifier.citationParmar G, Parmar S, Amin SS, Patel NB. A Study on Socio-Demographic and Clinical Profile of Patients on Second Line Anti-Retroviral Therapy Registered at ART Centre in Surat City. National Journal of Medical Research . 2025 Jun; 15(2): 164-169en_US
dc.identifier.issn2249-4995
dc.identifier.issn2277-8810
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/252795
dc.languageenen_US
dc.publisherMedsci Publicationsen_US
dc.relation.issuenumber2en_US
dc.relation.volume15en_US
dc.source.urihttps://doi.org/10.55489/njmr.150220251102en_US
dc.subjectSocio-Demographic Profileen_US
dc.subjectClinical Profileen_US
dc.subjectSecond Line Anti-Retroviral Therapyen_US
dc.subjectART Centreen_US
dc.subjectHIVen_US
dc.titleA Study on Socio-Demographic and Clinical Profile of Patients on Second Line Anti-Retroviral Therapy Registered at ART Centre in Surat Cityen_US
dc.typeJournal Articleen_US
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